تحميل "Benefits & Risks of Peptide Therapeutics for Physical & Mental Health"

In this episode, I explain the major categories and types of peptides currently in use for therapeutic purposes. I discuss peptides for improving tissue rejuvenation and repair, promoting longevity, improving muscle growth and fat loss, and boosting mood, vitality, and libido. I explain the biology of how these peptides work and both their potential benefits and risks. I also discuss peptide sourcing, dosages, cycling, routes of administration, and how peptides work in combination. This episode will help you better understand the rapidly expanding landscape of peptide therapeutics and how to evaluate if specific peptides might be advantageous towards achieving your physical or mental health goals. Thank you to our sponsors AG1: https://drinkag1.com/huberman Mateína: https://drinkmateina.com/huberman Levels: https://join.levelshealth.com/huberman2/?partner=HUBERMAN Joovv: https://joovv.com/huberman LMNT: https://partners.drinklmnt.com/free-gift-with-purchase?rfsn=6327528.ecaabe8&rfsn_cn=EXCLUSIVE+GIFT+FOR+THE+HUBERMAN+LAB+COMMUNITY Momentous: https://livemomentous.com/huberman Social & Website Instagram: https://www.facebook.com/unsupportedbrowser Threads: https://www.facebook.com/unsupportedbrowser Twitter: https://twitter.com/hubermanlab Facebook: https://www.facebook.com/unsupportedbrowser TikTok: https://www.tiktok.com/@hubermanlab LinkedIn: https://www.linkedin.com/in/andrew-huberman Website: https://www.hubermanlab.com/ Newsletter: https://www.hubermanlab.com/newsletter Journal Articles Gastric pentadecapeptide BPC 157 accelerates healing of transected rat Achilles tendon and in vitro stimulates tendocytes growth: https://onlinelibrary.wiley.com/doi/pdf/10.1016/S0736-0266(03)00110-4 Gastric pentadecapeptide body protection compound BPC 157 and its role in accelerating musculoskeletal soft tissue healing: https://link.springer.com/article/10.1007/s00441-019-03016-8?error=cookies_not_supported&code=dca4f867-4002-47ba-8238-37e57cb5f8f6 Modulatory effects of BPC 157 on vasomotor tone and the activation of Src-Caveolin-1-endothelial nitric oxide synthase pathway: https://www.nature.com/articles/s41598-020-74022-y?error=cookies_not_supported&code=eb70c0b4-3e76-41b8-8a60-e669915d2647 Stable Gastric Pentadecapeptide BPC 157 and Wound Healing: https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2021.627533/full Insulin-like growth factor 1 (IGF-1): a growth hormone: https://bit.ly/43WpDaN MK-677, an Orally Active Growth Hormone Secretagogue, Reverses Diet-Induced Catabolism1: https://academic.oup.com/jcem/article/83/2/320/2865101?login=false Two-Month Treatment of Obese Subjects with the Oral Growth Hormone (GH) Secretagogue MK-677 Increases GH Secretion, Fat-Free Mass, and Energy Expenditure: https://academic.oup.com/jcem/article/83/2/362/2865156?login=false Kisspeptin signalling and its roles in humans: https://bit.ly/4cBfMeh Age-Related Changes of the Pineal Gland in Humans: A Digital Anatomo-Histological Morphometric Study on Autopsy Cases with Comparison to Predigital-Era Studies: https://www.mdpi.com/1648-9144/57/4/383 Huberman Lab Episodes Mentioned Dr. Natalie Crawford: Female Hormone Health, Fertility & Vitality: https://www.hubermanlab.com/episode/dr-natalie-crawford-female-hormone-health-fertility-vitality Dr. Michael Eisenberg: Improving Male Sexual Health, Function & Fertility: https://www.hubermanlab.com/episode/dr-michael-eisenberg-improving-male-sexual-health-function-fertility The Science of How to Optimize Testosterone & Estrogen: https://www.hubermanlab.com/episode/the-science-of-how-to-optimize-testosterone-and-estrogen Timestamps 00:00:00 Peptides 00:03:20 Sponsors: Mateína, Levels & Joovv 00:07:44 What is a Peptide?, Effects 00:12:06 Peptide Sourcing, Lipopolysaccharide (LPS) 00:14:48 Rejuvenation & Tissue Repair: BPC-157, Angiogenesis 00:21:50 BPC-157 & Tissue Injury; Mode of Delivery 00:27:53 BPC-157: Safety, Doses, Cycling, Tumor Risk 00:35:16 Sponsor: AG1 00:36:43 Tissue Repair: Thymosin Beta-4, TB-500 00:40:49 Growth & Metabolism: Growth Hormone, IGF-1, Risks 00:45:25 Secretagogues, Sermorelin, Tesamorelin, CJC-1295 00:52:21 Sponsor: LMNT 00:53:44 Ipamorelin, Hexarelin, GHRP-3, MK-677; Risks & Timing 00:58:69 Peptides for Growth Hormone & IGF-1, Risk; Combinations & Dosing 01:06:12 Longevity: Thymosin Beta-4, Epitalon (Epithalon) 01:12:09 Vitality: Melanotan, PT-141 (Vyleesi), Risks 01:17:21 Vitality: Kisspeptin 01:21:46 Peptides, Potential Benefits, Side-Effects & Risks 01:24:19 Zero-Cost Support, Spotify & Apple Reviews, Sponsors, YouTube Feedback, Momentous, Social Media, Neural Network Newsletter Title Card Photo Credit: Mike Blabac - https://www.blabacphoto.com/ Disclaimer: https://www.hubermanlab.com/disclaimer