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00:00:05
hi hello guys I’m
00:00:07
very glad to see you all and but today is the
00:00:10
last lesson of this month but I
00:00:13
still have some feeling like you know
00:00:15
what you’re missing on
00:00:18
protein biosynthesis and
00:00:20
you know what you’re missing lie down task
00:00:22
1 hour type of protein biosynthesis so on
00:00:25
Tuesday I I will hold an open webinar,
00:00:27
it will be for everyone, but first of all, Ivan will
00:00:29
wait for his students and we will
00:00:32
solve the tasks of the
00:00:33
first part on protein biosynthesis, how do you like
00:00:37
this idea, if you like it,
00:00:39
write something in the comments and
00:00:42
I will be very glad to see you all if you
00:00:44
can’t this is the time, well, the phase, after all,
00:00:47
you are calculating your time, you can
00:00:49
look at the recordings later, well, of course, I
00:00:52
will always be glad to see you that you
00:00:54
answered questions with me
00:00:57
so before the regulation of protein biosynthesis, we in
00:01:01
practice at the very end yesterday discussed what is
00:01:04
here there is one regulator it
00:01:07
synthesizes it encodes a repressor protein,
00:01:10
for example, this repressor protein
00:01:12
attaches to a structural gene and
00:01:16
this structural gene stops
00:01:17
being expressed, that is, it stops
00:01:19
working what time is it
00:01:21
always at 5 o’clock always at 5
00:01:24
o’clock who can’t look at the recording
00:01:27
guys, it’s okay,
00:01:30
but be sure to look like
00:01:32
this ok,
00:01:36
well, today we are moving on to a very
00:01:40
very delicate topic, I started
00:01:42
gametogenesis, we’ll see, then
00:01:43
we’ll look at embryogenesis and look at the embryo
00:01:46
too,
00:01:47
and
00:01:49
so gametogenesis, what is a gamete,
00:01:54
again on Tuesday we will look at the
00:01:57
task 1 hour, type of protein biosynthesis,
00:02:02
so x guys, what is a gamete gamete this is a
00:02:07
germ cell
00:02:13
here gametes sex cells
00:02:20
sex cells
00:02:22
sex cells what are the types
00:02:26
of eggs these are usually female sex
00:02:30
cells
00:02:33
there are sperm and
00:02:40
sometimes all with perm
00:02:43
remember how they differ from permeate
00:02:46
sperm in sperm unlike
00:02:48
sperm are immobile
00:02:51
and
00:02:54
sperm are motile in sperm we can
00:02:57
find in some plants sperm and
00:03:00
are found only in gymnosperms,
00:03:01
angiosperms, and
00:03:08
angiosperms, sperm in all others, there is
00:03:11
still such a moment in males, now
00:03:15
we’ll talk specifically about animals, in
00:03:17
males, gametes develop in the testes, and
00:03:20
in females, gametes, these cells develop in the
00:03:24
ovaries, and now we will talk to
00:03:26
you about the
00:03:27
formation of gametes specifically in animals
00:03:31
because in plants there all gametes are
00:03:34
generally formed by mitosis and all the words
00:03:37
gametogenesis let’s analyze its gametes, we already
00:03:40
know that these are sex cells din with
00:03:42
genesys always means that something is
00:03:44
formed genesis the formation of something
00:03:54
so that means there will be the formation of
00:03:56
sex cells let's look at these processes,
00:03:58
gametogenesis can be divided into
00:04:01
spermatogenesis
00:04:02
when guess what
00:04:06
sperm are formed, it is clear from the name itself
00:04:08
and Avagyan with here about the vagina,
00:04:12
eggs are formed in another way Avagyan with you can be
00:04:15
called again - with this synonyms you can
00:04:19
say so so then don’t ask
00:04:22
me about one of can I say it again -
00:04:25
s
00:04:26
thank you very much
00:04:29
Dasha thank you so now let’s analyze separately the
00:04:35
spermatogenesis of Homer her and Avagyan s and
00:04:38
compare them with each other
00:04:40
spermatogenesis it all starts with the primary
00:04:44
germ cell, here it is the
00:04:47
primary germ cell it has a set of
00:04:50
chromosomes 24 c as if it already has
00:04:54
replication occurred then this is the primary
00:04:57
germ cell, we will call
00:05:00
it for short p p k divides by mitosis divides by
00:05:03
mitosis once the sperm of that one is obtained
00:05:06
not with a set of chromosomes two n 20 these
00:05:11
sperm of that one do not divide a second time but
00:05:14
pay attention to this sperm of that
00:05:16
one to enter into a new mitosis you
00:05:20
still need to double the genetic information,
00:05:22
so right before mitosis, the sperm of that one does
00:05:25
not become two 4c, this is possible, that
00:05:30
is, in fact, the sperm of that does not happen 2 in
00:05:31
2 c puts on two people 4c, depending on what
00:05:35
period of life you look at them, before
00:05:37
replication or after, but most often on the Unified State Exam
00:05:40
they write exactly like this, but I’ll show you
00:05:43
one task where you have to write
00:05:45
exactly like that, well, in the end we got
00:05:49
four sperm from that unknown thief of chromosomes
00:05:51
two n 20 then these sperm from that one
00:05:56
get into the growth zone and a
00:06:00
first-order spermatocele is formed a
00:06:04
first-order spermatocele has a
00:06:07
set of chromosomes 2 and 4 c, that is,
00:06:09
replication has already occurred here, then this
00:06:12
spermatocele is growing, growing, due to
00:06:15
what, due to what, it will increase
00:06:17
in size, what needs to be done in general,
00:06:21
as with a person, when a person grows or
00:06:24
increases in size, it’s
00:06:26
okay when a person this is another
00:06:28
multicellular thing that is growing well, it is the
00:06:30
spermatocele for it to grow there must
00:06:32
be more content, so to speak, it
00:06:36
needs to synthesize more
00:06:38
nutrients Nastya is absolutely
00:06:40
right, it needs to create more
00:06:42
nutrients
00:06:43
due to this it grows and
00:06:46
increases in size, that is, essentially
00:06:49
replication occurs in the growth zone and in
00:06:52
general, the interphase is actively proceeding,
00:06:57
taking into account the interphase occurs then
00:07:01
this is already number 2 sperm of the first
00:07:05
order, that is, it was the primary germ
00:07:07
cell, then the sperm to go will not give
00:07:11
perma, then one is full of the first order, then
00:07:16
this spermatocele of the first order means it
00:07:19
enters mejos goes first first
00:07:22
division of meiosis
00:07:23
as a result of the first division of meiosis we
00:07:26
get two cells with a set of chromosomes
00:07:29
n2 price we form that after the first
00:07:32
division of meiosis there is a reduction in the
00:07:34
set of chromosomes but the mustache temple 2
00:07:36
ramative therefore 20 so we got
00:07:40
these cells, they are also called sperm
00:07:43
tacitus and but they are already cannot be also of the
00:07:45
first order will not be older than the
00:07:47
spermatocele of the second order, then the
00:07:50
spermatocele of the second order enters into
00:07:53
mejos 2 in the second division of meiosis and
00:07:56
there is already a divergence of these two
00:07:59
aromatic and chromosomes nadh and templetivnye
00:08:01
and we see a decrease in the amount of DNA and the
00:08:04
set of chromosomes becomes inter and
00:08:08
these cells are already called sperm tiger
00:08:12
and then these sperm ti de enter the
00:08:16
next zone it is called the zone
00:08:17
of formation here
00:08:20
the tail is simply formed due to the fact that the tail is formed
00:08:24
for called
00:08:25
formation and so spermatogenesis four
00:08:29
zones of reproduction when there is a primary
00:08:32
germ cell begins to divide mitoses and
00:08:34
we get a lot of sperm that is
00:08:37
not the next growth zone when a
00:08:40
first-order spermatocele is formed and it grows,
00:08:44
this is logical into the growth zone, tons grows
00:08:47
then the maturation zone of maturation when
00:08:50
he still needs to make his own set of
00:08:52
chromosomes so more sexual,
00:08:54
more haploid, reduce it by two
00:08:58
times then here meiosis should occur
00:09:00
1 second division and the first second
00:09:03
division refers to the zones of maturation
00:09:05
dragged along, as it were, zones of maturation two
00:09:07
stages occur the first stage when
00:09:10
the first mejos occurred and we got
00:09:12
sperm tacitus and the second order and the second
00:09:15
stage when the second meiosis occurred and
00:09:18
we got spear motives and everything and then the formation zone here are
00:09:23
your questions what you don’t
00:09:26
understand here is how to remember this we take there is the
00:09:29
same as we acted in life
00:09:31
cycles the same as we performed laughs
00:09:33
we take a leaf we
00:09:35
prescribe first by peeking
00:09:38
you can even look at the coals completely looking at the
00:09:41
webinar then close it
00:09:43
prescribe it slightly peeking then
00:09:47
close it again, draw again,
00:09:49
don’t peek, but if at some
00:09:52
point you need to look, you understand
00:09:54
that you didn’t remember it, look again
00:09:56
and so on until you can
00:09:59
draw it without peeking three or four
00:10:01
times, draw and spermatogenesis will take place
00:10:04
in your pocket everything is clear, generally a
00:10:07
fun easy topic and even logical at
00:10:09
first not like quantitatively multiplied
00:10:12
multiplied by mitosis of course this is all
00:10:14
done in the house increased in size
00:10:16
interphase and then you need to reduce the set of chromosomes
00:10:20
but they all mature that way, that
00:10:22
is, logical well
00:10:28
no primordial germ cells that’s what the
00:10:30
primary ones are called, that’s it, that’s the
00:10:32
very first one that doesn’t have a manner, it’s
00:10:35
called the primary germ
00:10:37
cell, and the sperm of that one already appears
00:10:40
after the division of the primary germ cell,
00:10:45
so
00:10:47
good now about vogue, thank you, Pasha,
00:10:51
thank you very much about everything, I’m very glad
00:10:53
that you have everything works out now both
00:10:56
genesis about the
00:10:58
buoy from the formation of eggs, here
00:11:02
everything will be very similar to spermatogenesis
00:11:04
sea from the difference, the beginning is the same zone
00:11:07
of reproduction here the primary germ cell
00:11:10
divides by mitosis and here we see that there
00:11:13
are more of them and we get
00:11:16
about a carriage with a set of chromosomes 220 now
00:11:19
each in the car enters the
00:11:23
growth zone where it increases in size
00:11:26
for
00:11:28
we get an oocyte of the first order
00:11:30
which grows in the vagina for the
00:11:33
growth zone are more pronounced than in spermatogenesis
00:11:37
spermatogenesis because the eggs
00:11:39
must contain more
00:11:41
nutrients and therefore here it grows
00:11:44
stronger than in the growth zone of
00:11:48
spermatogenesis, so
00:11:53
then this first-order oocyte
00:11:57
enters the maturation zone, and look, the
00:12:00
first difference was that the vacek
00:12:02
turns out to be larger, the second difference in the maturation zone,
00:12:07
the oocyte enters 1 mejos,
00:12:11
enters 1 mejos, and
00:12:15
here there is a difference, the
00:12:18
divergence to divide cytokinesis will
00:12:21
occur unevenly and drainage
00:12:23
of spermatogenesis cytokinesis occurred
00:12:25
evenly, half of the cytoplasm and
00:12:29
half of the cell into the other and you see it turned out 2
00:12:31
identical cells top ovo genesis of the sex
00:12:35
more than half of the cytoplasm will go into one
00:12:39
cell and just a little bit of the cytoplasm
00:12:42
will go into another cell and this is the cell
00:12:44
that received most of the
00:12:47
cytoplasm
00:12:48
most of nutrients, be
00:12:51
this the color of the second order, but this
00:12:54
second cell, a poor little one with a
00:12:57
small amount of cytoplasm of
00:12:59
nutrients, will be called a
00:13:01
polar body, also known as a director for and
00:13:05
bodies, aka reduction, these are all
00:13:08
synonyms for a director for it is also called a
00:13:13
director for and
00:13:15
or reduction
00:13:21
why couldn’t I share pores, what do
00:13:24
you think, why is Vova genesis such a
00:13:27
perversion, what was it necessary to do, so
00:13:30
this polar body will
00:13:32
not be able to become an egg in the future
00:13:35
for which the polar body sacrificed
00:13:39
all its nutrients,
00:13:41
gave everything everything here for what your
00:13:45
guess will be invented, we think
00:13:51
egg 1 yes well, this is rather a
00:13:54
drawback that women have so few
00:13:56
eggs, it would be possible to have
00:13:58
more, but what is all this for? 7 it’s
00:14:02
all for the sake of the family so that in
00:14:06
the end the egg receives just a
00:14:09
drop-dead supply of nutrients
00:14:11
so that it has a lot of
00:14:13
nutrients because the
00:14:18
future embryo will need to be fed with these nutrients until
00:14:22
it is implanted into the uterus, it will need to be
00:14:25
fed somehow,
00:14:27
but if these are some other
00:14:31
organisms in which
00:14:33
fertilization occurs in a non-organism, there in
00:14:35
general the egg should be just
00:14:37
gigantic, remember what it looks like The
00:14:39
egg of the fish there is so large that it is so
00:14:42
large
00:14:44
because in them fertilization
00:14:46
occurs generally from the outside and it is in the
00:14:48
embryo that needs to be fed; it
00:14:51
feeds on the nutrients of the
00:14:52
egg, we have smaller eggs
00:14:54
because development occurs in the uterus and the
00:14:58
embryo begins as soon as it is implanted in the
00:15:00
uterus receive
00:15:02
nutrients from the mother, so we all
00:15:04
return here, the maturation zone as
00:15:07
a result of the first meiosis, we get
00:15:09
two cells, one very large, which
00:15:12
has grabbed most of the nutrients for itself,
00:15:13
it will be
00:15:15
called this second order with a
00:15:17
set of chromosomes m2 c and the second one is from God and
00:15:20
polar bodies with a set of chromosomes n20
00:15:24
she donated her
00:15:26
nutrients further and the larger the dowry
00:15:30
when we don’t have a bride here with a
00:15:32
dowry then the second division of meiosis
00:15:36
again this second-order oocyte
00:15:40
divides again and we God again
00:15:43
unevenly and this is the egg that
00:15:46
turns out to be large
00:15:48
with large amount of
00:15:50
nutrients, but this polar body
00:15:53
is small, and this polar body is
00:15:55
also divided into two,
00:15:57
so it will be small
00:16:00
because initially the cell was small and
00:16:02
what we have as a result are both
00:16:05
genesis from the 1st cyto of the first order,
00:16:09
or you can even drip further from 1 and
00:16:12
the car we get one egg and a
00:16:17
circumpolar body, but in gamete
00:16:20
genesis from one spermatogenesis we
00:16:23
got four full-fledged
00:16:25
sperm,
00:16:27
this is the story of
00:16:29
this egg, we are also writing here either
00:16:34
with eggs because amati yes if abate yes
00:16:36
it can still happen later what
00:16:40
changes will come only then will
00:16:42
the egg cell come, but there is no formation zone here, you
00:16:46
see sperm has sperm then Guinness
00:16:49
there was a formation season when
00:16:51
the tails were formed, as you understand,
00:16:54
the eggs are east, no, they
00:16:57
have opinions, so there will be no formation zone here
00:17:00
either,
00:17:02
but this is the story here,
00:17:05
now there is
00:17:06
one more nuance where they catch children
00:17:10
just harshly v.g. in
00:17:13
most vertebrates, in the
00:17:16
second division of the meiosis of the oocyte of the second
00:17:19
order, here
00:17:22
everything stops, here everything
00:17:25
stops for us from the second order
00:17:28
and
00:17:29
when fertilization occurs,
00:17:32
the sperm fertilizes this one
00:17:34
from the second order, such an immature one, and
00:17:38
only after fertilization
00:17:40
does everything else in the process happen
00:17:43
and we we get
00:17:47
an egg in this way,
00:17:49
the sequence could be an
00:17:53
oocyte of the
00:17:55
second order
00:17:58
of fertilization and
00:18:00
only then
00:18:02
the formation of an egg,
00:18:06
this is the nuance
00:18:08
it is written in the mansion, it is stamped pink and
00:18:12
this question was in the trash, in my opinion it was
00:18:15
even at a real giga I don’t remember exactly, but
00:18:17
in a rock club it definitely there is 21 years old I’ll find it
00:18:19
later I’ll show you keep this in mind don’t confuse
00:18:23
what function the polar corpuscles perform,
00:18:27
firstly they are just like that, they
00:18:30
are formed
00:18:31
as a
00:18:33
by-product you are all such yeast, you need to
00:18:36
strip it, you need to separate it, they also
00:18:39
accept the fate they help the eggs to be
00:18:41
directed, that is, the guide on the
00:18:43
corpuscle helps on units what
00:18:45
directions in such a function are also
00:18:47
prescribed, but the most important thing is that they
00:18:49
are simply like a remnant of this and
00:18:51
the eggs,
00:18:57
so what is watts and look,
00:19:01
they can talk to you about you and about the car,
00:19:04
they can write this down as about this
00:19:08
synonyms wow
00:19:10
equals about it’s just that so, so they can
00:19:14
say no, don’t be scared,
00:19:17
now the difference is here the cell
00:19:22
grows stronger than here in ovogenisa from the
00:19:26
1st year of spermatogenesis we get 4
00:19:30
sperm from one sperm
00:19:33
4 sperm from 1 and in the car I get one
00:19:37
egg and 3 guide bodies and
00:19:41
everything is also spelled out here: the sperm of that person does not
00:19:43
begin to actively divide at
00:19:47
puberty and this process goes on continuously,
00:19:50
that is, the process of spermatogenesis in
00:19:53
boys begins at
00:19:55
puberty, before that nothing happens in them,
00:19:59
but in girls they are laid
00:20:02
at the stage of the embryonic period, that is,
00:20:06
when the girl was still in
00:20:09
her mother’s tummy, in her womb, she was already
00:20:15
laid in the car for loss, and then when the girl
00:20:20
enters puberty, from
00:20:23
that moment on, every month,
00:20:26
one egg begins to mature, only
00:20:28
one per month, but in the car, everything is already
00:20:31
laid, so there is such a joke that the
00:20:35
grandchildren
00:20:37
were already in the grandmother’s belly, that is, they
00:20:41
were already in the grandmother’s body because
00:20:44
the pedal is not a joke, it’s true because
00:20:46
the grandmother is a daughter in her and the daughters are already about the
00:20:49
car which in the future will turn into a
00:20:53
child
00:20:54
into a grandson,
00:20:57
yes, in men the process of spermatogenesis with
00:21:02
without if there were no pathologies, it
00:21:04
occurs until death, as
00:21:08
the teacher said, until
00:21:09
the last breath,
00:21:10
and in women, the maturation of eggs
00:21:13
occurs before menopause, which usually
00:21:16
occurs
00:21:17
from 45 to 55 years, somewhere at this
00:21:21
age, the formation of
00:21:24
eggs ends and,
00:21:26
accordingly, the childbearing
00:21:28
period ends for a woman,
00:21:34
so what
00:21:37
if the girl is infertile, well then the
00:21:40
grandson will not be destined to be a tradition of
00:21:45
grandchildren, as it were, they were conceived but were not born,
00:21:48
so to speak
00:21:50
further, we will analyze this point in the
00:21:54
process of spermatogenesis, 4
00:21:57
gametes are formed from 1 and in the carriage the axis and simplification of
00:22:01
sperm are not
00:22:06
in the process about the vagina, only
00:22:09
one gamete is formed from one about the carriage and
00:22:17
for the vagina for a very important
00:22:19
remarkable thing, the final
00:22:21
process of genesis is completed only
00:22:24
after fertilization, this
00:22:27
is typical for vertebrates, that is, first from the second
00:22:30
order, then fertilization, only for the
00:22:32
same reason we can call it
00:22:34
complete egg, although sometimes this is
00:22:37
neglected and they say that
00:22:40
ovulation has occurred, the egg has entered the
00:22:42
fallopian tube, although it has not yet been
00:22:44
fertilized, and there are such and such
00:22:47
inaccuracies in this matter, but
00:22:50
spermatogenesis and everything is simply formed by a
00:22:52
second-order spermatocele from sperm
00:22:55
to sperm and that’s all and only then
00:22:58
fertilization
00:23:01
why infertility is formed oh even you
00:23:05
of course raised such a pressing topic for a
00:23:07
huge number of reasons it could
00:23:10
be the absence of ovulation
00:23:12
it could be due to the fact that for example a
00:23:14
woman was exposed to radiation and all
00:23:17
her eggs turned out to be ineffective
00:23:20
they all died or picked up mutations
00:23:24
due to radiation these all of her in the carriage,
00:23:27
accordingly, there
00:23:30
will be no more healthy eggs
00:23:32
then there
00:23:34
may be something with the uterus, that is, everything is
00:23:38
fine, she ovulates but the uterus is not
00:23:40
capable of receiving, that is, the
00:23:44
embryo does not implant into the uterus,
00:23:47
this may be the reason for a man 50
00:23:50
percent of problems with the flesh related to
00:23:52
mobility,
00:23:54
more on the male side, it could be a
00:23:57
violation of sperm motility, a
00:23:59
violation of the activity of
00:24:01
sperm enzymes, and so on,
00:24:05
about ectopic pregnancy Ksyusha, I
00:24:08
will show you because I have
00:24:10
a picture for that, let’s
00:24:13
do this task, establish the
00:24:15
sequence of stages about vaginismus she
00:24:18
without a catch, it seems that everything here is usually
00:24:21
try it yourself,
00:24:23
so let’s see that there is the formation of
00:24:27
first-order compartments, the formation of qi
00:24:29
cells, mitotic division, the horse of me
00:24:33
your associate of fathers thoats and you, but
00:24:36
first of all, let’s choose curtains,
00:24:41
choose fire and methodical division in the
00:24:45
fire f
00:24:47
thirds long ago write immediately give a complete answer
00:24:50
not to the first point directly give a
00:24:52
complete answer, then it will be
00:24:54
unclear who
00:24:57
who belongs where what
00:25:00
so methodical division fire and they
00:25:03
divided
00:25:04
then oocytes of the first order are formed
00:25:11
oocytes and the first order grow the growth of
00:25:14
oocytes and accumulation of nutrients
00:25:18
then the
00:25:22
fathers of the first order must enter
00:25:25
in mitosis and meiosis, acetate of the first order
00:25:29
results in the formation of flowers of the second
00:25:31
order and
00:25:33
this leads to the formation of eggs and
00:25:36
polar bodies
00:25:40
315 462 yes, good, you lox are super,
00:25:47
now let's look at the structure of the gametes,
00:25:51
what we got by finishing off is missing a little,
00:25:54
no big deal,
00:25:56
sperm we get sperm
00:25:58
with tails what they are made of
00:26:00
the sperm secretes the head the middle
00:26:03
part or neck it can be the neck and
00:26:06
the tail from the
00:26:08
head there is the nucleus itself the most valuable thing
00:26:12
that needs to be brought into the egg there
00:26:15
is genetic information from the
00:26:17
father
00:26:19
half of the set of chromosomes the child will have
00:26:22
from the father and that’s exactly what it is located
00:26:25
now there is a haploid set,
00:26:26
then in the head there is also an ohm color, and the
00:26:31
beauty contains a bunch of enzymes that
00:26:34
will help break down the shell of the egg and
00:26:37
penetrate inside without color and
00:26:40
the sperm will suit the cassie cells and everything
00:26:42
will not be able to pass into it because it is
00:26:45
well protected from 1 ohm is a
00:26:48
derivative complex racer why
00:26:51
namely the golgi complex remember
00:26:53
what function the golgi complex performs
00:26:58
what is the function of the complexes more
00:27:02
ayman tina just not the lysosomes but the
00:27:05
complex howling on the complex the complex is
00:27:08
more capable of forming just
00:27:10
lysosomes are produced you write correctly
00:27:13
and
00:27:14
the bolt contains a large number of
00:27:16
enzymes because the golgi complex it
00:27:18
converts proteins into enzymes and
00:27:22
packages them in lysosomes and,
00:27:24
accordingly, these enzymes are actively formed by color;
00:27:29
in the neck there is a large number of
00:27:32
mitochondria, that is, all the mitochondria
00:27:34
that were in the cells move here,
00:27:37
here they are not and the tail of the tail is
00:27:42
necessary; due to its contractions,
00:27:45
the sperm moves, there are
00:27:48
a lot of mitochondria here are needed
00:27:52
in order to release energy
00:27:54
for the contraction of the tail in order to
00:27:58
carry out its motor activity,
00:28:00
so we looked, now let’s look
00:28:03
at the egg, here
00:28:05
it is, the egg does not secrete a whole
00:28:08
bunch of shells, which, in general, for
00:28:11
wigwams you don’t need to know, but for general
00:28:13
development we have listed it here which
00:28:16
contains the nucleus and in the game there will be
00:28:18
another half of the genetic
00:28:20
information
00:28:21
that the child will get from the mother, there
00:28:24
are islands of plasma, both plasma is like
00:28:27
cytoplasm, only the cytoplasm of the egg
00:28:29
and the veins are the
00:28:31
exact shell with a supply of
00:28:33
nutrients quite
00:28:35
impressive, the transparent shell, the
00:28:38
corona radiata and all these the
00:28:41
sperm will have to
00:28:45
overcome the membranes in order to overcome them, he
00:28:47
uses the enzymes that were
00:28:50
in his colors, these enzymes begin
00:28:53
to break down this membrane, in fact, at
00:28:56
this moment a huge number of
00:28:58
sperm
00:29:00
are working to break down this membrane,
00:29:03
and indeed, to break down this
00:29:05
membrane, a large number of sperm are required,
00:29:06
but only one penetrates
00:29:12
only one penetrates inside and at the moment of
00:29:15
penetration
00:29:16
it throws off its neck and tail, it
00:29:19
all falls off and only
00:29:21
the head with the nucleus penetrates and
00:29:23
now there is such a nuance where all the
00:29:26
mitochondria remain, all the mitochondria of the father where
00:29:30
they will remain
00:29:36
so
00:29:39
where do you think the mitochondria went after
00:29:43
all, the mitochondria are for you
00:29:45
there is also genetic information in the mitochondria, there
00:29:47
is ring DNA with
00:29:50
genes that encode
00:29:53
mitochondrial enzymes and the
00:29:55
sperm are left
00:29:57
outside and in the end all the mitochondria
00:30:01
that go to the child they go to
00:30:04
him are maternal, so our DNA of our
00:30:09
mitochondria is all maternal and therefore
00:30:13
mitochondrial diseases are transmitted
00:30:15
only from a woman, so at our
00:30:17
university we had a lecture
00:30:21
on biochemistry which was called
00:30:23
mitochondrial diseases and the teacher
00:30:26
wrote in parentheses or again
00:30:28
women are to blame for everything,
00:30:30
so in general all our mitochondria
00:30:33
only come to us from a woman
00:30:35
because the sperm and while
00:30:38
their mitochondria penetrated the egg we lost everything
00:30:41
and that’s how fertilization happened,
00:30:45
this is my old photo of you guys,
00:30:49
you also had this, but
00:30:52
now, probably, no one
00:30:54
took a photo
00:30:58
about the corona radiata about
00:31:01
the corona radiata, this is one of the membranes
00:31:04
that the sperm needs to overcome
00:31:06
and guys, the sperm
00:31:08
always penetrates alone even if the
00:31:10
result is twins and still only
00:31:12
one sperm, how
00:31:14
twins are obtained later I’ll tell you,
00:31:16
so only one sperm
00:31:19
will penetrate even when twins are what
00:31:24
can cause twins to occur right away, I’ll
00:31:26
tell you there are two eggs, you know this, you are
00:31:29
twins, fraternal
00:31:37
fraternal twins occurs
00:31:40
if it so happened that a woman
00:31:42
accidentally ovulated two eggs at once,
00:31:44
that is, initially there are two
00:31:47
eggs, this event is very rare, but
00:31:50
this can happen and,
00:31:52
accordingly, one egg
00:31:53
is fertilized by one sperm,
00:31:56
2 eggs are fertilized by another
00:31:59
sperm, we will get 2
00:32:04
different yawns,
00:32:06
this one will have a set of thomson tm strokes and this one
00:32:10
just 2 and 3 genetic information
00:32:13
they will have completely different from different
00:32:14
eggs and from different sperm
00:32:16
they will be as different as
00:32:19
children
00:32:21
born in two different pregnancies can be different and
00:32:25
there are identical twins
00:32:31
when there was one egg it was
00:32:35
fertilized by only one
00:32:37
sperm and
00:32:40
everything turned out it seems to be normal and a
00:32:42
zygote, but then something goes wrong and it
00:32:44
doubles and
00:32:46
bifurcates, you get 2 zygotes, but
00:32:49
since they had the same set
00:32:52
of chromosomes, everything was the same because
00:32:54
from one cell these are from one
00:32:55
sperm, these are identical twins
00:32:58
genetically identical and they are born to
00:33:02
them they will be genetically identical if
00:33:05
one grows up to be fat and the other one is thin,
00:33:09
it’s not because this one has
00:33:12
no predisposition to be overweight,
00:33:15
they are genetically identical and it’s just that one
00:33:17
ate more or he got more food
00:33:20
and 2 were fed little, that’s why one became
00:33:23
fat, the second remained thin, but
00:33:27
these two may have different genetic
00:33:29
information, 1 may have a genetic
00:33:31
predisposition to obesity, the other does
00:33:33
not, they are fraternal twins, in general,
00:33:35
this is the story, and now where
00:33:40
does the fertilization process take place, which means the
00:33:42
brass egg is formed in the ovary at
00:33:46
the time of ovulation in a girl, it comes
00:33:49
out here in an hour there were such in the carriage and
00:33:52
they ripened ripened ripened,
00:33:55
such a follicle appears, it grows,
00:33:59
grows, grows every month and at one
00:34:01
moment bursts and the egg comes out into the
00:34:05
fallopian tube, so it gets into the
00:34:07
fallopian tube, but in 3 then the uterus ovary
00:34:11
uterine tube the ovary is connected to the uterus of the
00:34:14
fallopian tube, meanwhile, if the
00:34:20
sperm enters the uterus, they
00:34:23
enter the fallopian tube and
00:34:25
fertilize the egg;
00:34:27
fertilization occurs in the
00:34:29
fallopian tube; if it is all
00:34:32
fertilized, then this zygote
00:34:39
begins to descend
00:34:41
through the fallopian tube into the uterine cavity;
00:34:45
at this time, growth in the uterus increases the endometrium is
00:34:48
such a thick layer of ideal tissue, it is
00:34:52
so lush and allows the
00:34:55
zygote to easily immerse itself, it
00:34:59
immerses itself in it, and at this moment
00:35:01
we say that pregnancy has arrived,
00:35:03
then this zygote begins to
00:35:06
grow into the uterus,
00:35:09
but it is no longer a zygote
00:35:11
it will be a small embryo and is already beginning
00:35:14
to grow and divide and turn into the
00:35:16
future child of a
00:35:21
neighbor for identical paladins, for different
00:35:25
think the gender may also be different,
00:35:27
so another option is if
00:35:31
ovulation occurred, the egg came out into the fallopian
00:35:34
tube
00:35:35
and the sperm did not come, well, there was no
00:35:38
sexual intercourse there, for example what then this
00:35:42
egg comes down here, this
00:35:45
endometrium, people are all upset that we
00:35:48
came here and no one was waiting for us, and
00:35:51
this endometrium begins to come out,
00:35:55
the egg exfoliates, too, and all this comes out in
00:35:58
the form of bloody discharge, which
00:36:01
is called menstruation
00:36:03
before and this happens every month
00:36:06
after some about a
00:36:09
week and a half after ovulation,
00:36:11
she was still hoping for a few days
00:36:14
before the sperm had given, and if not, then no,
00:36:16
it begins to exfoliate,
00:36:17
so about an ectopic pregnancy,
00:36:21
ask in what case this happens
00:36:23
if, after all, the sperm fertilized
00:36:25
the egg, and for example, the woman had
00:36:28
frequent inflammatory processes, what -
00:36:31
and then the fallopian tube narrowed due to inflammatory
00:36:34
processes, well, there
00:36:35
were some kind of growths or something else or some kind of
00:36:38
mucus was too thick here and
00:36:41
this embryo got stuck here and that’s it, and then
00:36:46
this enlargement begins, you
00:36:48
have to do an operation removal of the
00:36:50
fallopian tube to remove this
00:36:53
embryo, that is, this situation is unpleasant,
00:36:55
to save such a pregnancy, as far as I
00:36:57
know, it is impossible how a miscarriage occurs,
00:37:01
a miscarriage may also have different reasons,
00:37:04
one of the implantation is disrupted, in the
00:37:07
early stages, before I tried, for example,
00:37:09
to implant, but something went wrong and
00:37:12
everything goes higher
00:37:14
there is a long story about miscarriages and what
00:37:18
boys boys will listen to is
00:37:20
firstly boys we have the majority of
00:37:22
future doctors here secondly they will have a
00:37:25
wife and daughter you still need to understand how
00:37:28
all this happens
00:37:31
if the fallopian tube is removed
00:37:34
a woman will be able to get pregnant because
00:37:36
she has there is one more fallopian tube 1 month
00:37:39
this ovary ovulates for the second month this
00:37:41
ovary and for a month when
00:37:44
this ovary will ovulate we can
00:37:46
get pregnant on this side we can’t
00:37:48
get pregnant anymore here is a
00:37:57
separate webinar on the opposite to come out
00:37:59
even then the funder everyone let’s now at
00:38:03
least one of course yes it’s useful, it’s
00:38:05
interesting, but there’s also a
00:38:08
long story about miscarriages, let’s look at
00:38:10
this task in the twenty-seventh task,
00:38:13
which could also be, but
00:38:16
lately they haven’t been introducing
00:38:18
gametogenesis 27, well, we have to be
00:38:21
ready for anything, the somatic cells of the
00:38:23
Drosophila fly are contained in 8 chromosomes,
00:38:27
determine the number of chromosomes and DNA molecules
00:38:30
in cells during spermatogenesis in the
00:38:34
reproduction zone and at the end of the maturation zone of
00:38:37
gametes
00:38:39
Karina asks how to find out which month is
00:38:42
which ovary, but this can be seen on an ultrasound,
00:38:45
firstly, and secondly, some women
00:38:48
feel directly on which side they feel
00:38:50
when they have ovulation occurs, not
00:38:53
everyone can clearly say this,
00:38:56
I have this ovary today Fowler's shaft
00:39:11
somatic somatic these are not sexual
00:39:16
they are sexual it is always when they
00:39:20
give it to you they mean 22 c that is, the
00:39:22
original in the original
00:39:24
somatic cell was a set of us sun two and two
00:39:27
prices, which is equal to 8 chromosomes, 8 DNA molecules,
00:39:34
this is somatic and since this always
00:39:37
needs to be remembered, determine the number of
00:39:39
chromosomes and DNA molecules in the
00:39:42
reproduction zone and at the end of the maturation zone, the reproduction
00:39:53
zone, the reproduction zone, we have about the carriage and
00:39:59
and the carriage usually has a set of chromosomes 2 m
00:40:03
20 this 8 chromosomes and 8 DNA molecules I really do
00:40:08
n’t like this task because they
00:40:10
don’t specify
00:40:12
exactly what period before replication and
00:40:15
after replication in the answer that they
00:40:17
indicate in the reproduction zone 88 before, that
00:40:20
is, here they usually did
00:40:23
not indicate anything, but they think that everything is
00:40:27
simple into the fire it is 22 c and at the end of the
00:40:30
gamete maturation zone at the end of the maturation zone
00:40:33
when the entire mejos
00:40:42
set of chromosomes has already occurred there will be n.s. this is only
00:40:46
half as much
00:40:47
28 divided by 2 will be 4 chromosome and 8 dna is
00:40:53
half as much as 4 dna
00:40:57
answer justify what processes
00:41:00
occur in these zones the
00:41:02
reproduction zone somatic cells are
00:41:05
divided by mitosis therefore the
00:41:08
same somatic cells are formed or a set of monsoons is the
00:41:11
same as the somatic
00:41:12
zone maturation goes mejos I will learn here
00:41:16
I wrote that ago the sperm of that
00:41:19
one is formed and the
00:41:25
maturation zone goes mejos therefore at the
00:41:28
end of meiosis haploid
00:41:30
cells are formed as reduction
00:41:33
division occurs until
00:41:35
the next one, this task is to determine the
00:41:37
number of chromosomes and the number of DNA molecules in the
00:41:40
chicken car before division begins here
00:41:46
we will need the information that you and I
00:41:48
wrote that a carriage has a set of
00:41:50
chromosomes two n 20, but if you are asked
00:41:54
right before division, it means that
00:41:56
replication has already occurred and they we will
00:41:59
assume that they come on at 4 s, this is the
00:42:01
case when the carriage and will already have
00:42:05
a set chromosomes and DNA 424 prices and in the
00:42:10
first-order compartment and the first-order chain
00:42:12
has a set of chromosomes 2n 4c
00:42:17
let's see how they wrote the answer the number
00:42:20
of chromosomes in the carriage before division 2-4 prices
00:42:24
this is observed because fire and deepoy are
00:42:27
not but the number of DNA molecules before division
00:42:30
doubles if they didn’t write to you
00:42:33
before division, then you would write 2 of this
00:42:36
price
00:42:37
the number of chromosomes in the first-order compartment is
00:42:40
24 c this is observed because the
00:42:43
first-order oocyte is formed from a dipole
00:42:45
and fire I as a result of me who for and the number of
00:42:49
DNA molecules before division was doubled like
00:42:53
this quite simply very similar
00:42:58
to the topic of mitosis and meiosis, well, let’s
00:43:02
look again at fertilization, how it
00:43:04
happens, here it is, an egg, an egg
00:43:07
consists of various egg membranes, a
00:43:11
cytoplasmic membrane and cytoplasm, which is
00:43:14
also its plaza, here it is a sperm with a
00:43:17
head, a neck and a tail, the
00:43:19
head has a color and contains
00:43:23
enzymes enzymes break down the
00:43:25
shells of the egg and sperm
00:43:28
china it will penetrate into the personal
00:43:31
space of the egg
00:43:34
Nastya will be here the
00:43:37
sperm penetrates there and
00:43:40
throws off its tail along with the neck and
00:43:43
together with its mid-hunts and then the
00:43:47
nucleus of the egg and the nucleus of
00:43:49
the sperm begin to merge with each
00:43:53
other and
00:43:54
if each was haploid, then after the
00:43:57
merger we get that we get a yawn
00:44:01
with a diploid set of chromosomes,
00:44:03
what happened to them next and then
00:44:09
embryogenesis will begin,
00:44:12
fertilization has occurred, we have turned out and
00:44:15
a year,
00:44:16
let’s first introduce such concepts
00:44:19
to you as ontogenesis and embryogenesis
00:44:23
ontogenesis is the individual development of the
00:44:26
organism from the formation of the zygote
00:44:31
until death,
00:44:35
the grave is like this
00:44:37
and
00:44:38
until death,
00:44:45
ontogenesis is and this is the history, let’s say, of the
00:44:48
entire life of a particular organism of mine,
00:44:51
yours, and so on, but
00:44:53
this is all ontogenesis,
00:45:01
embryogenesis is the individual development of the
00:45:04
organism from yawning to birth, this is
00:45:11
embryogenesis, that is, embryogenesis
00:45:15
is part 1 before the first stage of ontogenesis,
00:45:27
well, I see that if I see that there
00:45:30
was some question about it, you already noted
00:45:32
that everything is
00:45:33
so good,
00:45:37
now
00:45:39
we will talk to you today about
00:45:42
embryogenesis in great detail, and so its
00:45:45
egg then begins
00:45:48
to split up, but it’s necessary now from
00:45:50
a single-celled state it will turn into a
00:45:52
multicellular no, no, we were then
00:45:55
all our lives in this zygote, we consist of
00:45:57
many cells, how did this happen,
00:45:59
the zygote begins to divide, first it
00:46:01
divided once, then the second time one
00:46:05
of them divided, it turned out to be two cells, but
00:46:07
here this technique is unusual, this is how it
00:46:10
divides all mitosis but there is no
00:46:14
increase in the number of
00:46:17
cells increasing in size court this
00:46:22
cell divided but the cells do not grow
00:46:24
then divided again already four
00:46:26
cells turned out there again dad and
00:46:29
divided already 8 cells again 16
00:46:32
cells we still get a morula and 16
00:46:35
cells and the morula is the same size the
00:46:39
same as the zygote since the cells did not grow in the
00:46:41
interphase, such a peculiarity is
00:46:45
that in
00:46:47
this process of crushing it, you between the
00:46:52
methods of the interphase contained only during the
00:46:55
period there was replication, but
00:46:58
this accumulation of
00:47:00
nutrients and all this did not occur, the
00:47:03
throat inside is
00:47:05
all filled, but then a
00:47:09
cavity appears in this module and when
00:47:12
such an empty space appears there,
00:47:14
this already causes a blastula,
00:47:16
so the first stage is called
00:47:20
fragmentation between divisions,
00:47:23
there is a short interphase consisting
00:47:25
only of a period, so the total mass
00:47:28
does not change, it is divided once again
00:47:31
and again it turns out to be a morula, then an
00:47:35
empty space begins to appear in the module
00:47:37
and we get the same
00:47:39
bubble, this is a blastula, the first stage
00:47:42
of etching leads to the appearance of a blastula, a blastula
00:47:45
is a single-layer embryo, a
00:47:51
single-layer embryo,
00:47:57
this is the moment that I wrote to you,
00:48:00
be sure to remember the enemy of the catch was about
00:48:02
this question, he is right on this
00:48:08
I paid my attention, that is, there was a question, what is the
00:48:10
specific feature of the division in the image of the
00:48:13
transformation of the blastula,
00:48:15
what happened next with this bubble, it turned
00:48:18
out like this in the eye,
00:48:20
here is one layer of cells, you can
00:48:22
draw it like this,
00:48:31
you have a round and
00:48:34
then this bubble, this blastula
00:48:38
begins to protrude just
00:48:41
imagine if you have a ball, you
00:48:43
pierce the output and it begins to swell and
00:48:46
one side is absorbed like this 0
00:48:48
platform show here we see
00:48:53
a blastula and one wall ends
00:48:56
inward, it is pumped in and we already get a
00:49:00
two-layer embryo consisting of an
00:49:03
outer wall and an inner wall
00:49:07
which has a cavity was inside the blastula, it was
00:49:09
called the blastocoel,
00:49:13
then we had one wall moving back and
00:49:18
from a single-layer embryo the embryo
00:49:21
became a two-layer one, it has an outer
00:49:24
wall called ectoderm
00:49:28
and an inner wall called m, then the
00:49:32
dermis is also the endoderm, yellow
00:49:35
ectoderm, blue
00:49:37
and it will always be something internal
00:49:40
act outside what we have in this hectare
00:49:44
this stage is called gastrula in it we
00:49:47
highlight the
00:49:49
cavity that is inside but it
00:49:52
will no longer be called it was become it will be
00:49:55
called gastro goal or in another way it is
00:49:58
called the gastrula cavity from not eat
00:50:02
the primary intestinal will further develop a
00:50:04
cavity
00:50:06
in the future, but this is a hole
00:50:09
like this, a hole has formed here,
00:50:13
this is a blast, I wanted them to tour, but
00:50:18
we are all called by the blast chord, this is confusing, we have to come to
00:50:20
terms with it, the
00:50:23
mouth will develop from it, and now such a
00:50:26
moment if
00:50:29
from this there was astapor and the
00:50:32
mouth actually develops, there will be a mouth in the future, then this is the
00:50:35
primary genus and the
00:50:38
genus and animals, and if such a misunderstanding occurs from this
00:50:42
primary mouth
00:50:44
and an
00:50:47
anus is formed and the
00:50:52
genus begins to break through on the other
00:50:56
side, then we call such people a secondary genus,
00:51:00
but this is a secondary mouth and we are secondary mouth
00:51:04
and who belongs to whom we will talk at
00:51:07
the factory about this primary secondary mouth and
00:51:10
we will come back
00:51:12
yes
00:51:14
yes we got awkwardly where the
00:51:18
mouth should have been we went wrong
00:51:22
so gastrula means we got the condition of
00:51:25
the fire remembering what we had we had
00:51:27
yawning is already up to one cell, then we
00:51:31
had a morula, for some reason it constantly
00:51:34
ignores it, so we immediately write the eye tula
00:51:37
blastula, then a single-layer embryo, one
00:51:40
layer, and now we got the gastera
00:51:44
gastrula consists of two layers, which then the
00:51:47
gastera begins further and
00:51:49
it changes in all sorts of ways here
00:51:53
it happens firstly
00:51:55
from the ectoderm from the outer layer, here
00:51:59
cells begin to divide, a
00:52:01
neural plate appears, here it
00:52:04
is, the neural plate, then this is
00:52:07
the neural plate, here it begins
00:52:09
to bend and eventually turn
00:52:13
into an additional tube from this
00:52:15
neural plate, in the future the
00:52:17
neural plate will be formed tube, which
00:52:22
means the entire nervous system will develop from it, that’s
00:52:25
all that concerns the
00:52:27
nervous system, it could be the
00:52:30
brain, it could be the
00:52:35
spinal cord, the
00:52:39
spinal cord, nerves,
00:52:41
analyzers, receptors, and so on, but also
00:52:45
similar to what is obtained from what tissue is the
00:52:48
neural plate formed from a barrel from
00:52:51
what leaf from the act or and order of
00:52:55
nervous tissue is formed from the ectoderm and
00:52:59
therefore further we will say that the entire
00:53:01
nervous system is formed from the ectoderm,
00:53:09
well done, remember this moment, this is
00:53:11
already a hint for you when you teach
00:53:13
what is formed from which germ
00:53:15
layer, this will already help you well, that’s
00:53:18
all with the neural plate, we figured out
00:53:20
that then
00:53:24
some new cells begin to appear from the endoderm, new
00:53:27
cells that
00:53:30
will subsequently accumulate here and
00:53:34
another layer of mesoderm is obtained and a
00:53:38
notochord is formed from the mesoderm, and the
00:53:41
horde map also has a normal
00:53:44
origin from the notochord. develop
00:53:48
[music] the
00:53:49
axial skeleton of the bones and all the derivatives of the
00:53:52
bones, well, in the end we see that all this is
00:53:56
also from the mesoderm, called
00:53:59
the endoderm, it also curls up here into a
00:54:02
tube and
00:54:04
from this endoderm the intestines will develop there
00:54:05
and so on and some
00:54:08
internal organs, that is, the endoderm
00:54:10
will lining us practically from the inside,
00:54:13
the ectoderm covers us from the outside, plus the mesoderm
00:54:16
will form its own nervous
00:54:18
system from it, such an intermediate
00:54:20
layer,
00:54:21
look that the endoderm inside forms
00:54:25
such a cavity, this cavity will be the cavity of the
00:54:27
primary intestine or the primary cavity, and
00:54:31
here these are similar, this primary cavity
00:54:35
has already arisen, a landmine is truly here it is
00:54:37
only it has changed a little here,
00:54:39
so if they ask you where the
00:54:41
primary cavity was formed, you
00:54:43
say not in no roll, you say that
00:54:45
it was formed already on tour, so it was
00:54:48
already there, that it
00:54:51
changed there a little bit, but the secondary cavity is
00:54:54
formed here in the mesoderm and it
00:54:56
is formed as you see in the nerve they are
00:55:00
formed into nerves Nastya yes she now
00:55:03
we said it
00:55:05
then we got three germ
00:55:09
layers three main ones this is the
00:55:12
blue ectoderm this is this yellow
00:55:15
endoderm and mesoderm from the mesoderm we also
00:55:18
got a notochord and from the ectoderm
00:55:21
we got a neural plate which
00:55:24
then will turn into a neural tube, then
00:55:29
tissues will begin to develop from these germ layers, acquired the process of
00:55:32
tissue formation, call them histogenesis
00:55:35
because histology is the science of tissue
00:55:38
places with this tissue and the
00:55:42
science of
00:55:47
leaf tissue this tissue and well, diss to gain
00:55:50
with genesis something is formed places
00:55:53
of tissue, then some organs begin to appear from these tissues,
00:55:55
this process
00:55:58
is called organogenesis or the process of
00:56:00
organ formation, and then
00:56:03
various organs of the system appear which of which
00:56:06
germ layers you need to know, but you don’t
00:56:09
know by and in almost every
00:56:11
variant,
00:56:12
well, not in every via variant they give
00:56:15
this task to correlate the ectoderm
00:56:17
of the endoderm, for example, with the guitar and
00:56:21
such sects of the dermis are formed by the epidermis of the
00:56:25
skin,
00:56:28
that is, the ectoderm to cover on the outside
00:56:30
means this is the epidermis of the
00:56:33
skin derivatives of the skin so derivatives of the skin
00:56:35
include sweat glands sebaceous glands
00:56:38
mammary glands
00:56:40
hair nails enamel of teeth nervous system
00:56:44
because we saw that from the ectoderm the
00:56:46
neural plate is formed, the
00:56:49
sensory organs they develop from the nervous system,
00:56:51
and also the pituitary gland and pineal gland from below, so
00:56:55
remember the endoderm is what lines
00:56:59
us from the inside, this digestive system, this
00:57:01
includes the respiratory system, the
00:57:06
digestive glands, the liver, the
00:57:08
pancreas, the thyroid gland,
00:57:11
then the
00:57:14
mesoderm, the middle layer, something then the middle
00:57:17
between our outer layer between the skin the
00:57:20
inner layer of the digestive system
00:57:22
there will be muscles bones bones from the notochord
00:57:25
blood and lymph tissue
00:57:29
fluid is formed this is all liquid connective
00:57:31
tissue cartilage ligaments and tendons joints
00:57:35
genitourinary system
00:57:37
testes
00:57:38
ovaries but testes ovaries this is the reproductive
00:57:40
system it was possible not to write this
00:57:43
because we have already written the genitourinary system,
00:57:46
this is just to draw your attention to
00:57:48
ford escort and
00:57:51
many, many things will develop
00:57:53
adrenal glands and dermis, please note that
00:57:56
our skin consists of several layers:
00:57:58
epidermis dermis
00:58:01
and
00:58:08
subcutaneous fatty tissue
00:58:11
subcutaneous fatty tissue fat
00:58:14
epidermis
00:58:16
is formed from ectoderm
00:58:18
dermis adipose tissue is formed from mesoderm;
00:58:21
fat in general is
00:58:24
mesoderm; fat can also be included here; even
00:58:28
if the tissues are
00:58:30
ectoderm, this is mainly epithelial
00:58:34
tissue, very often and nervous; here is the
00:58:36
epidermis of the skin; this cave
00:58:39
gland is also epithelium; nervous tissue;
00:58:43
these are nerves; pituitary gland; and it is difficult to drink from here;
00:58:46
endoderm too basically epithelium
00:58:50
epithelial tissue is found here
00:58:52
mesoderm is either connective tissue
00:58:55
such as bones blood and lymph or
00:58:59
muscle tissue such as muscles for example
00:59:03
so well what is mesoderm formed from
00:59:06
mesoderm begins to develop from endoderm cells
00:59:11
endoderm cells
00:59:13
know this by heart at the test one hundred
00:59:17
percent next month you will be asked in as
00:59:20
a result, cells with the same
00:59:22
genotype
00:59:24
acquire different specializations during the formation of an organism, that
00:59:26
is, you really have a question: why do we
00:59:29
even have the endoderm here,
00:59:31
all the cells are the same, why the
00:59:35
respiratory system will develop from one cell
00:59:38
and the digestive system will develop from another cell, the
00:59:40
question is that there are
00:59:44
different specializations
00:59:47
acquires cells in the process of
00:59:49
differentiation and in the differentiation of
00:59:51
embryonic cells,
00:59:53
different genes
00:59:56
in the chromosomes are activated in different cells and therefore synthesizes
00:59:58
different proteins, that is, the original
01:00:00
cell was not yet specialized, it
01:00:04
can be called like this, like a patent for
01:00:10
the potency of
01:00:14
Tati, this is like everything is a patent for and
01:00:19
perhaps it can become the future of any
01:00:20
cell, they can call it a stem
01:00:23
cell,
01:00:26
then if it is influenced by some
01:00:29
differentiation factors,
01:00:34
differentiation factor number one town,
01:00:36
genes are activated that allows it to
01:00:39
become a cell of the respiratory system,
01:00:42
if it is influenced by other differentiation factors,
01:00:48
then other genes are activated and it
01:00:53
becomes, for example intestinal cell,
01:00:57
this is how it happens
01:01:00
under the influence of factors, it may
01:01:03
not necessarily be hormones, it may also be
01:01:05
hormones, but also other differentiation factors.
01:01:10
Now let’s talk about the structure of the embryo.
01:01:13
You don’t have this in your workbook
01:01:15
because I added it after a
01:01:17
new collection of round and here is a
01:01:20
drawing of his head, I have everything
01:01:22
after this picture, if you need it, I
01:01:25
can make a separate one, like a
01:01:28
checklist, you can print it out in yourself in
01:01:30
addition to
01:01:31
what is here, there is an embryo, here he is
01:01:35
with me, he really looks like an embryo, he has
01:01:38
no yolk the sac has an umbilical cord, there
01:01:41
is an allantois
01:01:45
on the outside, the embryo itself floats in such
01:01:48
amniotic fluid,
01:01:50
the amniotic fluid is enclosed in, and to me, a
01:01:54
romantic bubble is obtained
01:01:57
from the outside, and to me, it has such chorionic villi,
01:02:01
here they are, chorion villi, and here the
01:02:05
largest villi form the place where
01:02:08
the placenta is formed, let's Let's figure out
01:02:11
what is what and why it is needed
01:02:14
Chora
01:02:15
root is outside the embryonic membrane, that
01:02:18
is, it develops into the embryo from the
01:02:20
uterus,
01:02:22
which contributes to the nutrition of the embryo and
01:02:25
takes part in the formation of the placenta;
01:02:27
they form villi that contribute to
01:02:30
attachment to the uterus, that is, these villi
01:02:32
seem to grow into the uterus,
01:02:34
allantois outgrowth the intestines of the embryo, that is,
01:02:38
that is, it develops from the intestines of the embryo,
01:02:41
ensures gas exchange and accumulates
01:02:43
excretory products in mammals,
01:02:46
also participate in the formation of the placenta
01:02:48
and umbilical cord
01:02:50
placenta, who will be the placenta, I’ll show it to you,
01:02:53
this is an embryonic organ that
01:02:56
is formed from the chorion and alan girdle and
01:02:59
provides nutrition and gas exchange as well as the
01:03:03
removal of harmful metabolic products and
01:03:05
forms a game to attack the amber barrier,
01:03:08
look what it all looks like here is the
01:03:10
umbilical cord hell will be up to the embryo
01:03:13
very similar to the
01:03:16
embryo
01:03:17
this is the uterus
01:03:19
this wall of the uterus and the
01:03:22
umbilical cord it comes in the choir but
01:03:25
these are chorionic villi and not densely
01:03:28
braided and blood
01:03:30
capillaries, but this is the mother’s blood and, as
01:03:33
a result, from the mother’s blood
01:03:35
nutrients enter the blood, which
01:03:37
is in the choir then, and these
01:03:40
nutrients pass through the
01:03:41
umbilical cord and enter the embryo, the
01:03:44
embryo feeds on this, but there is
01:03:47
such a barrier and not everything some substances
01:03:50
get into the blood of the child, for
01:03:53
example, harmful drugs, not
01:03:56
everyone passes through this barrier, this
01:04:00
barrier is called Dima then
01:04:04
placental by
01:04:07
whom is this the placental barrier from the word
01:04:11
heme, this is blood and the placenta, the placenta and
01:04:15
blood do not mix, therefore the blood of the
01:04:17
mother and the child does not mix,
01:04:23
yes, and this is really when a
01:04:26
woman gives birth to a child, she pushes, the
01:04:29
uterus contracts, first
01:04:31
the baby comes out, and then the woman is told that
01:04:34
let’s
01:04:35
push some more and the placenta comes out, the
01:04:39
placenta is just like the placenta, with all
01:04:42
this goodness, she must also be given
01:04:44
birth, so to speak, otherwise she It
01:04:47
will remain there and begin to rot, and then
01:04:49
inflammatory processes will begin there,
01:04:50
all of this will have to be removed surgically, this is the
01:04:53
story, and
01:04:56
also the
01:04:59
amnion, the amnion, this is also outside the embryonic one
01:05:02
about the difference in the blood types of the mother and the
01:05:07
child
01:05:08
about where we have such a central
01:05:10
barrier if the mother has a negative
01:05:14
blood type in the child
01:05:16
positive
01:05:19
I would like to tell you better about
01:05:21
blood groups because here we often
01:05:23
talk about antigens, let’s
01:05:27
tell you the project later, there will be a
01:05:29
Rh conflict, but this can be avoided
01:05:32
a little later, the project I’ll tell you
01:05:37
Diana, it’s true that if after the birth of a
01:05:39
child a woman encapsulates her
01:05:42
placenta, there will be take then there
01:05:44
will be more energy some do this they
01:05:47
take this placenta and and somehow dry it
01:05:49
crush it put it to rest pack it in a capsule by a
01:05:52
woman then drink it but from a scientific point of
01:05:55
view there is no evidence
01:05:58
that it is effective or useful so I
01:06:03
believe that this is
01:06:05
my opinion that it’s ineffective,
01:06:13
some people even fry it and eat it, but the background is
01:06:16
normal meat, it’s environmentally friendly,
01:06:18
why not eat it,
01:06:21
but the benefit will be no more than
01:06:24
good chicken or beef meat, it
01:06:27
even smells a little bit of cannibalism, but that
01:06:30
means to me
01:06:32
[music]
01:06:37
outside the embryonic membrane is filled with
01:06:40
amniotic fluid
01:06:42
it Firstly, it provides mechanical
01:06:44
protection for the embryo; it is water there and,
01:06:47
accordingly, even if something
01:06:49
presses on the woman’s stomach, it will not be
01:06:51
damaged there so much because it is in this
01:06:52
water
01:06:53
during childbirth, this amniotic sac
01:06:56
bursts and the amniotic fluid
01:06:58
comes out, you may have heard the
01:07:00
concept that the water is leaving and it is
01:07:03
just pouring out, this is the amniotic
01:07:05
fluid, this is an important sign
01:07:08
for reptiles, birds and mammals
01:07:10
and reptiles, not everyone is there with
01:07:14
reptiles, the question is the
01:07:16
yolk sac,
01:07:19
the yolk sac is used like in
01:07:22
mammals as a hematopoietic organ, but
01:07:25
basically its main function is the supply of
01:07:28
nutrients substances,
01:07:37
well, let’s see what it all looks like
01:07:40
if I see in the picture and in the photo
01:07:42
the structure of the cat’s uterus with an embryo during
01:07:45
pregnancy,
01:07:47
so there is this, as you understand
01:07:50
during childbirth, the embryo is in
01:07:54
you, it’s not there, but there’s such a film outside
01:07:57
and inside there is liquid
01:07:59
according to number 3, the allantois is depicted from a
01:08:02
small area that
01:08:04
passes into the placenta according to number 6, the placenta
01:08:09
according to number 4 is the yolk sac,
01:08:12
in which, in addition to the
01:08:15
embryo, nutrients are also stored
01:08:19
according to number 5, this is a pathological
01:08:21
formation of a hematoma, as if from
01:08:23
dried blood, and
01:08:25
well, yes everything in general, everything is clear, clear
01:08:30
on the window, no luck, maybe
01:08:34
not the future, since he was photographed, who knows,
01:08:37
maybe he won’t be born fat anymore, well,
01:08:39
now let’s sum up what
01:08:41
happens in embryogenesis,
01:08:45
embryogenesis, in short, if without
01:08:48
details, then everything happens like that - then
01:08:52
then the blastula, then you can say first
01:08:55
the morula then the blastula, but the morula
01:08:57
is ignored in all tests; the blastula, the
01:09:01
blastula, occurs due to fragmentation,
01:09:07
then the gastrula,
01:09:11
then not the eagle, why is nervous called
01:09:15
nervous, why do you think the
01:09:17
nerve is the house of histogenesis, when
01:09:21
tissues and organs are formed, the
01:09:24
Guinness organ is no longer takes out
01:09:29
organogenesis, that's why there
01:09:34
is no nerve sophia hematoma and not everyone has it for some reason,
01:09:37
this cat got a
01:09:39
hematoma, apparently there was some kind of
01:09:40
bleeding, we also have a
01:09:42
hematoma anthem when we have such a canopy, you
01:09:45
know, with a lump there is a lot of dried blood,
01:09:47
this is also a hematoma when we have such a
01:09:50
bump in the hallway there, which means a hematoma, it’s
01:09:53
called
01:09:56
Daniel’s hematoma because the
01:09:58
neural plate begins to form there and the
01:10:00
rudiments of nervous tissue occur, the
01:10:02
nervous system appears, that’s why the
01:10:05
nerve is called
01:10:06
blastula, what kind of embryo is it single-layered,
01:10:10
double-layered or 3 layers
01:10:13
dominated by a single-layered embryo Gaspra
01:10:16
consists of two layers then there are acts of
01:10:18
the endoderm, and in it there is also a role in the
01:10:21
meat, a hole, a third layer, like this, in
01:10:26
general, follow along, don’t forget
01:10:28
that fragmentation is carried out by
01:10:30
mitosis, but between each division there is
01:10:33
no such full-fledged interphase,
01:10:36
yes, let’s now make this
01:10:39
stock exchange building that you they couldn’t stand it anymore, they wrote
01:10:41
the answer further with Sergey, they’ve already tied everything up
01:10:45
enough to endure, where do we start so here there
01:10:49
is
01:10:50
the formation of
01:10:52
meres,
01:10:54
you first have crushing and during
01:10:58
crushing you get blastomeres, these are
01:11:01
separate little things, right now I’ll show you what
01:11:03
exactly blastomeres are,
01:11:05
these little things are already blastomeres and
01:11:10
first blu-100 appears in measure only
01:11:12
then they are already formed into blastulas,
01:11:17
so this means the formation of blastomeres,
01:11:21
then
01:11:24
the formation of single-layer embryos or
01:11:26
blastulas, then the formation of
01:11:30
endoderm acts, this is the gastrula, then
01:11:33
the mesoderm appears in the neuron and already the
01:11:37
differentiation of tissues and organs, when
01:11:40
there are simple identical cells, we
01:11:42
begin to appear separately some
01:11:44
different fabrics that
01:11:46
differ from each other are
01:11:47
differentiated such and here four
01:11:51
315
01:11:53
24 well done, super well
01:11:58
if you didn’t do this then you weren’t
01:12:00
a child what is the last picture for you
01:12:05
well on this in general then the whole lesson was very
01:12:10
cool interesting and now guys in
01:12:15
general then we we are moving to a new stage,
01:12:16
very significant, we will move on to
01:12:18
genetics,
01:12:20
this is also just not that this is a special
01:12:24
life there, so to speak,
01:12:26
what on Monday we meet in
01:12:30
genetics on Tuesday, we will also
01:12:32
solve the task on protein biosynthesis for the
01:12:35
first part, if you need a
01:12:37
second part later on some
01:12:39
other Tuesday I’ll decide
01:12:42
for today it turned out to be a very fun
01:12:45
webinar about
01:12:46
everyone good luck in the tests Nastya about what
01:12:50
question
01:12:52
what question
01:12:55
please write again
01:13:01
when there will be evolution after genetics that
01:13:05
is, December is already December and January
01:13:09
if only one ovary
01:13:12
will also have menstruation but that is,
01:13:15
ovulation occurs, even
01:13:17
the egg is released and
01:13:19
then, accordingly, it cannot
01:13:23
be fertilized in any way since the sperm
01:13:25
will not be able to reach it because
01:13:27
there is no fallopian tube and the endometrium just begins
01:13:30
to peel off and a
01:13:32
period occurs, they will still be every
01:13:34
month but through meiosis 1 1 cycle
01:13:40
the woman will not be able to be fertilized because
01:13:42
the egg will not come out into the fallopian
01:13:44
tube that it is not there and in the second month
01:13:47
the egg comes out of the fallopian tube of everyday life and
01:13:51
on the other hand because there is a
01:13:53
fallopian tube and it can be
01:13:55
fertilized
01:13:56
task and about the chicken now
01:14:02
so
01:14:04
how many blocks are there Magomed in terms of
01:14:08
quantity, you need to calculate the exact figure, but I wo
01:14:12
n’t tell you, we still have genetics
01:14:14
and evolution,
01:14:15
anatomy and ecology, and everything
01:14:20
why there are no periods after childbirth, it
01:14:23
takes some time for the
01:14:26
hormonal levels to adjust, the woman immediately after
01:14:28
giving birth to the first carp, she just had a
01:14:31
huge surge there oxytocin increased
01:14:34
amount of progesterone during
01:14:36
feeding because of this, she does
01:14:38
not ovulate for some time until the hormones come to normal
01:14:41
and only then does ovulation begin after some
01:14:45
time,
01:14:46
usually this happens about
01:14:49
a year later, but for some it can be
01:14:51
much later
01:14:53
so about the chicken now guys, where is
01:14:56
this question
01:15:04
in the chicken carriage here they write to you
01:15:12
so determine the number of chromosomes and the number of
01:15:16
DNA molecules in the chicken carriage before
01:15:19
divisions begin, you and I know that there was a
01:15:23
primary sex cell with a set of
01:15:26
chromosomes in 14 c when the carriage is formed
01:15:29
they are formed by mitosis
01:15:34
is formed in
01:15:39
another carriage, but it could be
01:15:41
sperm of this kind, it doesn’t matter,
01:15:44
they are formed with a set of chromosomes in n20,
01:15:48
but since this is the reproduction zone, they
01:15:50
divide many times and these too
01:15:53
must divide again, but before they
01:15:56
enter the next mitosis they need
01:15:58
increase the set of
01:16:00
number of DNA molecules,
01:16:02
replication will occur, the set of chromosomes will become 2n 4c and
01:16:06
only now they will be able to enter the
01:16:10
next mitosis and therefore a new car will be formed
01:16:15
again with a set of chromosomes dn 20, that is,
01:16:18
immediately right before the
01:16:20
methodical division itself, they have to
01:16:22
increase the number of DNA molecules,
01:16:24
replication occurs therefore since
01:16:27
I’ll say here that right before the start of division,
01:16:30
then 2 and 4 c, and if this is not indicated, then it’s
01:16:33
like they haven’t just formed and there has
01:16:36
n’t been replication yet then write to two
01:16:38
20 I
01:16:39
even understood this moment
01:16:42
after today’s webinar everyone wants to
01:16:45
become a mint gynecologist now I think
01:16:47
that I I also wanted old people to become an
01:16:48
obstetrician-gynecologist for some reason, my
01:16:51
favorite field, but I’m not at the Faculty of Medicine,
01:16:53
so no,
01:17:00
everything is
01:17:02
fine then until Monday
01:17:08
I’ll try everything further that no, you don’t want to
01:17:12
become a gynecologist or it’s not clear
01:17:17
where the test will take place, your mentor
01:17:20
will call you,
01:17:22
but south video like this if you go to
01:17:27
52, in my opinion, there are poses and pediatrics, it’s very
01:17:30
problematic to go to gynecology
01:17:32
after just before the form, but after 52 you can
01:17:36
be a neonatologist, that is, a woman just
01:17:38
gives birth, expresses and the baby is immediately
01:17:41
handed over to you and you evaluate him there
01:17:44
how healthy he is, everything Is
01:17:47
he normal and so on,
01:17:54
this is also interesting, but after the
01:17:57
medical faculty of neonatologists it won’t
01:17:59
work out, and once again we have
01:18:04
genetics waiting for us, there are a couple more small topics, and
01:18:07
after genetics, such as selection, I drink
01:18:09
technologies and research methods, then
01:18:12
evolution,
01:18:13
then zoology, then anatomy and ecology
01:18:20
that such a section
01:18:27
of neonatologists is difficult, they are
01:18:30
born so small, they need
01:18:32
the size of a cat, they are really the size of a
01:18:35
cat, three and a half kilograms are born,
01:18:42
to be honest, I also gave birth to my
01:18:45
son, and I watched a lot of videos with
01:18:48
childbirth, and in the video they seemed like children... then
01:18:51
they are big and then my
01:18:53
child is born small, they are really lovely, they are so
01:18:57
tiny, in general it is very difficult with them,
01:19:00
they don’t talk and will tell you what is
01:19:03
wrong with them, but the pediatrician and neonatologists,
01:19:06
they are just mega people, they know a lot of
01:19:08
signals on how to understand what the child wants and
01:19:11
if there’s something wrong with him,
01:19:13
they can tell everything by reflex,
01:19:15
I just looked at them so oh my god
01:19:17
this is very cool bye
01:19:25
bye then if you have anything write and
01:19:29
ask questions

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