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Download "Live 19-29 #25 - L’INFLAMMATION ET SES 10 DÉCLENCHEURS – Partie1"

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Nutrition Fonctionnelle
Nutrition
nutritionfonctionnelle
inflammation
santé
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00:00:01
well I'm very late boa noite hello
00:00:07
good evening
00:00:09
he then begins to show you I
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'm not going to go back all the way from
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our introduction from the last time
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but still a little bit just to
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show you this photo which I
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spoke about the difference of
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acute information which simply means that we
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will initially have our friends with
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innate immunity who we were born with who will
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begin to act
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and this innate immunity is part
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of us it is considered completely
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physiological because when we have an
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acute inflammation either for I read
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rite a gimmick allergic reactions of
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trauma chip contusions sprains strains
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any infections
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all that is acute and we need
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sites to attack all that is to return
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that's it function of inflammation
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in a healing process
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on the other hand we have on the other side and there
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it is not the causes because here we
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can have causes as I
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told you d confirmatory elected but on this side
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there that's what I would like to alert
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what when we talk about Alzheimer's cancer
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depression rheumatoid arthritis of course
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we are talking about chronic inflammation
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but this chronic inflammation and the
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party of something of defenders that
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it is not done exactly autism,
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autoimmune disease, so we are going to make a
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feedback relationship, what do
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I mean by that, what is
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cardiovascular disease, what is autism, what is
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rheumatoid arthritis, what is
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depression, what are neurological diseases?
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will obviously feed they will
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die they will die it is a
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Portuguese they will feed
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the chronic inflammation but
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the chronic inflammation it can
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start from another trigger that I will
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present to you a few years and I will
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tell you so that you understand the
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situation well that the art of inflammation and
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gus we are going to call the 15
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it is not part of our work
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it is actually part of the action
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of doctors of pharmacists who will act
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to resolve this acute problem the big
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problem is 'the other side is the
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chronic side that it has unfortunately
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we have a body of professionals who
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will treat this
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chronic inflammation as if they were acute
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but it is not elected and the
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chronic and the low
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grade training which will have repercussions
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like some that I am
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showing you but I will
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show you others throughout this
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training but what I would like to
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explain to you is that our objective
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today is not to say that the
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disease has to arthritis everything that is
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its calf causes
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chronic inflammations scepter of all this is to
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show you that we have triggers
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I will present to you the turn of say
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that they will trigger all this is
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problematic there and for a
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health professional because you
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know that this China is designed
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for you health professionals and
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therefore it is there to show you
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the importance of this knowledge that is
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our objective
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I introduce myself I am and the hammers
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to naturopath dental surgeons
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worked and I show you from A to Z
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how to apply
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functional nutrition to transform your life
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and that of your patients we
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are here in this project which is called
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project 19-29 very easy we are there every
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Tuesday and every Thursday at 7 p.m. 8 p.m.
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that's why it's called project 19 29
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[Music]
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one like iron and acute
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and chronic inflammation these are complex reactions
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inseparable from the ace of the answer
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immune prevail its chronic
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and acute we have the immune response the
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problem is will it last
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will it persist if we have an
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acute inflammation with all all the
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stages that I showed you vascular
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cellular and repairs we will
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have an action for production on
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the other hand if we have chronic inflammation
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we will have a destructive action
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of agreement acute it will last a few minutes
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or a few days we install this
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acute inflammation
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adapted immediate short duration localized
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restorative protective for healing
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it is very important that you understand
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that very important and on the other hand we
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are going to see chronic inflammation which
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can take two weeks or years
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it is unsuitable we must not
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understand that chronic inflammation is
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welcome and the problem is that we
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start from the principle that the person has
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inflammation and instead of hall and
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the ideology of this information which
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are actually what triggers
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the inflammation we begin to treat
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the inflammation you want an example I
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will not give examples medical of the
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doctor no I will give examples
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of naturopath to the person he has a
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sinusitis she gives in plant the person
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with a fashion of throat she gives another
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plant they pretend phytotherapy but
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it's not at all that says all that there
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our about in
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functional nutrition in
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functional nutrition we are going to look for the cause the
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theologies of the problem and it is not
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to have why because you are going to
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give a herbal medicine you are going to
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have an intervention
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and what is going to happen it will
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come back and it will come back and there we enter
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into this chronic picture which is
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maladaptive which is of long duration which in
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general which is aggressive that it is not
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controlled and which fights ivan others or
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towards another interview its
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self-perpetuating sister is therefore certain that we
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will have all the quotes pathological situations
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included autoimmune diseases therefore the
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inflammatory reaction
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they are worth chronic without social security a
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sign that a sign what are we going to
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do it will lead us to cancer of
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the fries alzheimer diseases
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neurological diseases did not tell the team a
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cardiovascular disease and so on
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and so on I will speak to give
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the list however I am not here
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to give the list and explain
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each disease because that does not does
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not interest us have you already
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understood that all these labels have a
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common etiology which will concern itself
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with the label in bo it is to give
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a medicine it specific to each
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manager this is the medical protocol
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we have is not at all in the
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protocol not at all if you look
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here with Elise for a protocol you
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can leave there is no protocol
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there is reflection and through the
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biochemical reflection of the
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cause reflection is basics you will
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think and give a solution to the
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problem of your patience of your
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client is what you see the
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difference here I present to you the list
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in read it it is a weapon an article
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which shows exactly
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the chronically ill who ask who have
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chronic information as a source
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so we have Alzheimer's disease we have
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asthma or bronchitis we have acolytes we have
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one on Beijing we learn creative an
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alteration we have gathered your arthritis I
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am not going to read you everything and everything a young
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it's because it's Paris not repeating
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that there are several articles that they
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brought all these articles together and
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each article gave a
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different list and this height there he put them
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all together so we lose azima
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but we amass lite we have conjunctivitis
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we have squared the traffic of
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Chavez disease at the level of the heart we helped
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the psychologists we only have a serious lung
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we have I don't know what
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all this
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goes through information published
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chronicle so Do you understand
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that you are completely in the
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inflammation theme the problem is that it is
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a complex theme
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it is a theme which will require you to have a
00:10:09
very strong fundamental base you have to
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know everything that is innate immunity
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all that which is imitated adaptive the
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intellectuals who gave me 6/10 the summer regulator
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the lymphocyte all that is also everything
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with its parts memorization because
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everything makes sense the big question that
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will arise is what is the real
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problem
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why we all know what the real
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problem is, there remains a real problem to undermine
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the non-resolving inflammation, it is
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when we do not give a solution, a
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finalization of the inflammation, so there is
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this review which is called number
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of sheep. 'inflammation it is an
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extremely recent article 1
00:11:05
the non-resolving information is
00:11:09
a major driver
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tired of the disease but we can say
00:11:14
of the patients g12 this article there they
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showed us the mechanism and the
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consequences of this non-resolution of
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the inflammation and obviously here we
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are on youtube it is not a
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complete training so I know it I
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understand that perhaps it will leave
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a lot of holes in all my explanations
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and that is normal why because I am
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taking a piece of a training and I
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present to you and so sometimes it will
00:11:49
present itself in a very strange way I
00:11:53
show you for example here of another
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case who knows that we will see here in two
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parts a part of our
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higher resolutions and a part which are the
00:12:05
consequences of this non-resolution
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so you will see that there were
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perhaps terminologies that you do
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not know you want an example
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here for example
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infiltration by the
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suppressor cells of a coming law that is
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something that I don't know if you
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know who it's called imd so they
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are not exactly
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myeloid cells not at all they are
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cells which they go to delete the
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myeloid cells the premises if they
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were all in mireuil
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what does that mean because as at the origins the
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bone marrow are stem cells of the
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bone marrow unfortunately this mpcc cell
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of a family
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which comes from the cells of the
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stem cells but already infiltrated with
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people of problem why problems
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because this cell there will have an
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immonot activity suppressive rather than
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immunostimulating properties so we
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will see an infiltration of this type of
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cells at the level of unresolved inflammation
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when it is resolved we have our
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immune cells you understand
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perhaps you don't know that but
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it's more serious it' is not serious because we
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will gradually
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learn everything here we have, for example, made
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in philosophy cheap changes in
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macrophages I don't know if you know
00:13:41
afterwards we will talk about that we have two types
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of macrophages macrophages one
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macrophages of the same time the same
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thing for the lymphocytes and and when
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we do not have a change of chip of the
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macrophages we have unresolved information
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that is a subject where we will
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study macrophages logic 1 and
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type 2 macrophages
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after you also have a response and
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immune prolong excessive no
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men are inflammation or otherwise
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a response is normal we offer
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normality no resolution of
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inflammation you can also have
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a persistence a continuation a
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continuous estimate of microbes you
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want an example my patient has
00:14:38
irritable bowel syndrome and there such a
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beautiful one he has intestinal permeability
00:14:43
so I will have this simulation of two
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grain negative bacterial organisms with
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lps the ipo pack polysaccharides that we are going to
00:14:54
talk about later which will help me give
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this non-resolution inflammatory and
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therefore it is a trigger which we are going to
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discuss today this is what is
00:15:05
the microbiome a micro well the sound it is
00:15:09
all the microbes yacht but we can
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talk about a microbiota it is the
00:15:13
microbiota intestinal
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which is for example an
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important source of this
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inflammatory continuity there is also the
00:15:23
food allergens I am talking about 10 g
00:15:26
e but also what we call
00:15:31
allergies repair attentions it is the
00:15:36
bread allergies that you eat and you
00:15:38
start to clusters and that you are going
00:15:40
to have a quick and that you are going to
00:15:44
the hospital no it is another type
00:15:47
of immunoglobulin and gege which will give
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a delayed response of the clones to
00:15:53
examinations and that there is still a lot of
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vague regarding that the only thing we
00:15:59
know that we are sure is that they
00:16:01
have to freeze a food which
00:16:04
can pose a problem in terms of
00:16:07
repairing
00:16:09
hiccups so all these are a few
00:16:13
examples we will see as a conclusion a street
00:16:17
artist what is an inflammation of
00:16:21
the joint of a street have little to
00:16:24
do with osteoarthritis osteoarthritis with an
00:16:27
inflammatory connotation we can have
00:16:30
rheumatoid arthritis that there we will
00:16:33
see other parameters which will
00:16:36
also play localization and specific etc. we
00:16:40
will also see our famous inflammatory
00:16:43
bowel disease which are the patient j
00:16:47
inflammatory bowel which can
00:16:50
go through several labels
00:16:52
we have asthma we were going to multiple
00:16:57
sclerosis so we must not it is for that's
00:17:00
what I hate all labels because
00:17:04
leicester multiple sclerosis and
00:17:06
not the envelopes in thouars that's for sure
00:17:08
but not only that there are many
00:17:11
factors which will play such as for
00:17:13
example heavy metals such as for example
00:17:16
the inflammatory question but there are
00:17:20
genetic components components
00:17:23
are genetic and we have not finished
00:17:26
understanding because a student of this
00:17:29
disease we see that this disease
00:17:32
there are fourteen types of patients j
00:17:36
multiple sclerosis I have already had quite
00:17:39
a few patients with this
00:17:40
problematic problem there are some who
00:17:43
it will become acute quickly it is
00:17:48
perhaps linked to age is linked to
00:17:50
diet
00:17:51
so what we do in our work
00:17:54
is I do not am not crazy to say that
00:17:57
I am going to
00:17:59
completely stop leaving the roses in
00:18:02
patches because I there are several
00:18:04
types but I am going to accompany and I
00:18:07
am going to try to delay
00:18:10
this process as much as possible and I am also going to bring to
00:18:14
the maximum what it there is
00:18:18
positive vitality I am going to make a comment
00:18:20
regarding the information of the
00:18:22
diseases which is important
00:18:24
cancers cancers it is something
00:18:27
which scares me very much why because
00:18:29
there are professionals who do not does
00:18:31
n't realize and also does
00:18:33
anything with this concert of people
00:18:36
there is cancer who are
00:18:38
hormone-dependent cancer who are not
00:18:40
in the world dependent cancer who are
00:18:43
specific like prostate cancer
00:18:45
which should not be touched 7 prostate
00:18:48
there are other cancers that must be touched
00:18:50
finally if you are going to work on cancer
00:18:54
you must become a specialist you must
00:18:57
become if you want to become a
00:18:59
professional in functional nutrition
00:19:01
of people who have when it is
00:19:03
someone it is a cancer of everyone
00:19:05
which cancer you have to pay attention to the
00:19:08
choice of work that you have
00:19:12
obesity obesity it is a source to the
00:19:16
flames at war by by cy park which
00:19:20
obesity it goes through our
00:19:23
taxes site because we have
00:19:27
adipocytes of different types we have the
00:19:30
arms which have many many many
00:19:33
mitochondria which will increase our
00:19:36
metabolism but we also have the white which
00:19:40
will simply ingested ingurgitated
00:19:43
hamburg jt sugar through
00:19:46
your youth books and which will liberate
00:19:49
this famous bag inflammatory cytokines
00:19:52
example tnf-alpha intellectual king 6 we will have to
00:19:56
be all that because
00:19:58
you see yourself a TV no
00:20:01
seat it is produced by the
00:20:03
adipocytes
00:20:04
yes but the doors also produced by
00:20:07
the muscles by the muscle cells
00:20:09
during physical exercise so you should
00:20:13
not memorize things and say
00:20:15
anything that there is to bury it
00:20:19
no basis that it can be deleterious
00:20:21
but this same interview which 6 me is
00:20:24
why it will be released for for
00:20:27
help a trial this healing process
00:20:31
at the level of athletes who do a lot
00:20:33
of physical activities and which requires
00:20:36
a lot of muscle and so we have to be
00:20:39
careful all that we have
00:20:43
obstructive pulmonary diseases we have
00:20:46
atherosclerosis obviously
00:20:48
cardiovascular diseases without wanting to
00:20:51
complicate the story is that all this
00:20:53
we can have obesity linked to atherosclerosis
00:20:57
linked to cancer linked to everything will be linked to
00:21:00
all so I repeat I even saw
00:21:03
someone who spoke about a subject is
00:21:06
reduced to the information interests me I do
00:21:08
n't know who I him the vocal part and
00:21:11
the inflammation interests me because there
00:21:14
are cardiovascular diseases you
00:21:16
see we criticize the doctor a lot
00:21:18
but you do the same you are
00:21:21
always in the label that is why
00:21:24
these subjects must you don't be interested
00:21:27
because it's
00:21:28
cardiovascular diseases because you want
00:21:30
an example you can health professionals
00:21:34
take care of athletes with
00:21:37
excellent health ok
00:21:40
spare your journey with seven
00:21:43
athletes there are no women for example 30
00:21:46
years old she can have what a syndrome of
00:21:50
polycystic ovaries
00:21:51
and there what are you doing you
00:21:54
send seven people a doctor you
00:21:57
see if you don't need that
00:22:00
because it's information it's
00:22:02
hyper years underline me so you
00:22:05
do not go to treat CPR because that is what you
00:22:07
need to understand you will treat
00:22:10
inflammation through
00:22:13
functional nutrition
00:22:16
I hope that I have explained well
00:22:19
so
00:22:20
here I am giving you a walk through of the entire
00:22:25
inflammatory process but before
00:22:28
taking this journey with you there are
00:22:30
some definitions that you
00:22:32
absolutely must know
00:22:35
dance
00:22:36
then definition of sedan this milk of a
00:22:40
people I am going to do something to
00:22:43
be so that you take the things the
00:22:46
banks are fragments of molecules
00:22:50
which cause danger therefore from one of the
00:22:55
associates of moleque moleque their father
00:22:58
these two models model of forgiveness 10
00:23:04
Portuguese years of models of molecules which
00:23:07
are associated with danger but if you
00:23:10
want to make it simple it is fragments
00:23:12
of the molecules of danger
00:23:15
and the people the pints it is
00:23:20
fragments of pathogens example the
00:23:25
bacteria it will see
00:23:28
grain negative bacteria they will
00:23:31
have part of the membrane of
00:23:35
gram negative bacteria which is made up
00:23:38
of ipo polysaccharides sully
00:23:42
polysaccharides is a marker for a
00:23:45
receptor which will say wow this
00:23:49
bacteria is the big negative it a
00:23:51
problem from there that this receptor
00:23:56
which is called thomas
00:23:58
scepter 4 tlr4
00:24:02
it will spend what a family of
00:24:06
cytokines here we talk about the
00:24:09
interleukin cytokine family to an intellectual
00:24:12
quillan alfa- beta d'eliokem 18 33 36 36 beta
00:24:18
36 syfy 36 kid but what is
00:24:23
important for the moment for you is
00:24:26
that you will recognize
00:24:28
whatever there are the pathogens the
00:24:34
pieces of pathogens who knows and
00:24:36
example clps who has also two molecules
00:24:40
which are pathogenic and which have one of the
00:24:44
receptors which will recognize all this
00:24:47
to trigger an
00:24:50
inflammatory process ok we will look at that a little
00:24:54
bit
00:24:55
so initially we will have
00:25:00
an injury in damage and laws are the
00:25:04
jumps an example of in the
00:25:07
free radicals we have the whole family including the
00:25:11
quine 1 we bought hsp which are the
00:25:15
shock proteins we have there in so all
00:25:19
that can be considered as forms
00:25:21
example example of molecules
00:25:26
structures of the elements of fragments of the
00:25:29
molecules which can cause danger
00:25:31
said yes of course ok in the running nice for
00:25:35
example
00:25:36
ok that
00:25:37
's a guy without social security called
00:25:41
hangings so that we can communicate
00:25:43
so all that can possibly
00:25:46
become a danger for the bodies
00:25:50
so we're going to call dogs but we also have
00:25:54
the low peoples the peoples everything which
00:25:56
is a fact station infections example
00:26:00
and lps beach and line the
00:26:04
lhc or to the unemployed are the sugars of
00:26:08
cell walls the ipo paul sakaris and
00:26:12
an example all this will be received overview
00:26:17
by set of proteins which are called
00:26:22
prr and prr ckoi
00:26:28
dance recognition receptor and pumps what he
00:26:32
will see this type of pereire for
00:26:35
example macrophages the macrophages the
00:26:39
monocytes the macrophages that
00:26:41
unlike the monocytes and moc ofaj
00:26:43
quite simply the monocytes it is
00:26:46
in the blood circulation and the
00:26:49
macrophages it is a single site which has
00:26:52
left the blood circulation and it
00:26:56
will be fixed in a tissue and therefore we
00:27:00
can have for example a
00:27:02
cfyx macrophage in the liver it will be call
00:27:07
cells cuts make for example
00:27:10
it is he cuts it make it is a
00:27:13
mackerel fage fixed at the level of the liver we
00:27:17
have several macrophages which go last
00:27:19
in name and others which will not
00:27:21
win but which will still be fixed
00:27:23
to the above and therefore this macrophages zoom
00:27:27
on sector this receptor which will have
00:27:33
the capacity to recognize in pts to
00:27:37
recognize a people is there will do
00:27:40
what they will
00:27:42
I have not finished giving you other
00:27:44
examples of cells and which are
00:27:46
capable of to have it
00:27:49
would be sector mounted to the site
00:27:52
neutral macrophages our son the
00:27:55
nuclear polymorph why nuclear polymorph
00:27:58
because when you look at
00:28:01
the cell the elder in profile you will
00:28:05
notice that we drown and there
00:28:07
several lobules so it is rude
00:28:09
morpho several
00:28:13
death cism
00:28:15
us heart of the nucleus
00:28:17
that's why our sons
00:28:19
are called nuclear polymorphic
00:28:22
dendritic cells
00:28:24
and even lymphocytes all these
00:28:27
dendritic cells for example are
00:28:30
especially would give chic
00:28:32
b lymphocytes they are cells that we call
00:28:36
antigen presenters that makes all
00:28:39
the senses why which is mixed Monday
00:28:42
I have it is the recognition of clps the
00:28:45
recognition of all those of so
00:28:47
it will take that it goes to the level of
00:28:50
lymphocytes t they will present this
00:28:54
native is called epitopes epitopes
00:28:58
c it's this little piece of natives and
00:29:00
they will present to another type of
00:29:05
cells much more evolved and which will
00:29:07
also trigger
00:29:09
our adaptive immunity but you
00:29:13
can clearly see that through this
00:29:16
amp receptor is expended which have this
00:29:21
receptor all these cells is there the
00:29:23
problem the difficulty what there are
00:29:26
several proteins which are receptor
00:29:30
for recognition of slopes and dance
00:29:34
for example early the grid is louis
00:29:37
scepter there are fourteen types of sheet metal
00:29:41
accepted we talk and especially about
00:29:45
time the crisis is pts 4 because
00:29:48
he is at the level of the intestine he will
00:29:51
make known this gram
00:29:53
negative bacteria which has the lps but I do not have
00:29:56
others who are at the level not
00:29:59
only of the
00:30:01
season the arcep you m 'will like sea but
00:30:05
also at the olic site level there it is a
00:30:09
big chapter of the training
00:30:12
a term of inflammation and
00:30:15
receptors of all that there is in
00:30:19
llr p3c not likely scepter there are quite a
00:30:24
few things like the scepter that I have
00:30:27
not put 6 who are going to participate two sets
00:30:31
it is not Catholic street this vine
00:30:34
beyond concept there is aa I will tell you
00:30:37
later finally
00:30:39
other things prostaglandin Léon
00:30:42
against they know started all that
00:30:45
nf capable of activation of the neurons capable
00:30:48
and a transcription factor does not break them
00:30:50
all that is
00:30:54
inflammatory we will say like that and there
00:30:57
we will have the process of fargo cytos
00:31:00
it is phagocytosis look here the hypoxia
00:31:04
resolves in protest in may resin there we
00:31:09
are starting to network to
00:31:12
make the revolution that's why
00:31:15
there are levine networks and it's not
00:31:17
long since we discovered this
00:31:19
lgv network it's this group who are going to fargo
00:31:22
city and start our process of
00:31:24
healing
00:31:25
information and there we have there who have
00:31:30
registered in fact it is
00:31:35
cleaning and
00:31:37
repair we are going to return with the
00:31:40
king interiors which we call anti
00:31:43
inflammatory to which no Gilles
00:31:46
interests at km 37 there is a whole range
00:31:49
which because reduction of the nefs capable
00:31:52
catecholamines score all this will act and
00:31:57
I told you that my at the site
00:32:01
macrophages 1 transforms a
00:32:04
macrophages of it has a conversion 1 is
00:32:08
much earlier inflammatory and the
00:32:11
macrophages of 1/3 flames at war I
00:32:14
know it and you see that it is a
00:32:17
very complex subject that if you do not know
00:32:20
it will leave you with a lot of holes
00:32:22
and that is normal but you already have an
00:32:25
idea of ​​where you are going to go
00:32:30
so I told you about jeans
00:32:34
triggering the inflammation let's start
00:32:37
today with a few I do
00:32:39
n't know how many I wouldn't be able to
00:32:41
talk but already we're going to talk about the first
00:32:44
axis and the microbiome so if microbiome
00:32:47
at the checkout we have to say the
00:32:50
microbiome I put you six lots of
00:32:53
microbiota enmities between friends you
00:32:58
see clearly that I am not
00:33:00
inventing anything there is an
00:33:05
alliance that is super important
00:33:09
because in functional nutrition you
00:33:11
will need this notion of alliance
00:33:15
microbiota immune system
00:33:20
why because people look at
00:33:24
this sentence the microbiota play a
00:33:27
fundamental role in the induction in
00:33:30
the formation and functioning of the
00:33:32
immune system of the other I have to
00:33:35
stop if I say that you
00:33:38
understand well that if I I have a
00:33:40
pink double life what is a life with an
00:33:43
alteration in the quantity and
00:33:46
quality of the microbiota there I have heard
00:33:50
of for example intestinal microbiota
00:33:52
but I can also speak of the
00:33:56
vaginal microbiota I can speak of the bladder I
00:33:59
can speak of the two
00:34:02
upper airways all that there is microbiota
00:34:04
and there it is the same
00:34:07
no matter the bricks microbiota it is
00:34:10
fundamental in the coating the
00:34:12
formation and the functioning of the
00:34:13
immune system of the other those who
00:34:15
fight in this case we a return
00:34:19
the immune systems have largely
00:34:22
evolved as a means of maintaining the
00:34:26
social biotic reaction of the other
00:34:28
with the microbe so that means that
00:34:31
our immune system helps the
00:34:35
microbiota and the microbiota is our
00:34:38
immune system so this alliance
00:34:40
microbiota
00:34:42
immune protective response to
00:34:46
pathogens I give you an
00:34:49
example is that our master
00:34:51
microbiota if we are balanced in terms
00:34:55
of cult films and bacteroides summer
00:34:57
quantity of lactobacillus everything is fine
00:35:01
we have great positives which will be
00:35:05
greater than the quantity of grains
00:35:06
negative this grain positive these
00:35:09
commensal bacteria they will hockey and there is
00:35:12
no intestinal permeability
00:35:14
they will occupy
00:35:17
the glassware mucus they will be there to
00:35:21
occupy the barrier the first
00:35:24
intestinal barrier and therefore it will be a
00:35:27
sin mamac bacteria gram negative
00:35:30
to enter quite simply why it
00:35:35
will occupy the space quite simply already
00:35:39
to the mass
00:35:41
maintaining to see where the taking of the maintenance
00:35:44
of the tolerance to the harmless natives
00:35:48
hyper important because we have this
00:35:52
antigenic tolerance 1 when we talk about a subject
00:35:55
listened to it carefully we talk about
00:35:57
proteins and when we talk about proteins
00:36:00
we talk about food proteins so that's why we're
00:36:03
going to talk about
00:36:05
gliadin that's why we're going to talk
00:36:08
about glutamine that's for that we are going to
00:36:10
talk about all this hla protein which
00:36:13
can at a given moment
00:36:16
exceed this tolerance
00:36:19
why because I have a 10 bios you
00:36:23
understand by tolerating on the theme I am
00:36:26
already talking I have a problem of what
00:36:30
maintaining a regulatory view of
00:36:33
tolerance to harmless natives,
00:36:37
that's it and why is that elisa because
00:36:42
perhaps there is an overuse of
00:36:45
antibiotics
00:36:46
and there I come back to our problem
00:36:49
of treating
00:36:53
acute and chronic inflammation as if it were elected
00:36:57
there is a consumption below 1
00:37:01
which bio chick bios these intimate lives life
00:37:07
you will kill not only the
00:37:10
bacteria which sometimes is not even there it is
00:37:12
an inflammation of
00:37:16
normal physiological immune response that I do not understand
00:37:19
why the person takes
00:37:23
antibiotics with an excuse two
00:37:27
secondary infections good ok and there she
00:37:32
takes biotics for the long term
00:37:35
what will happen the micro good
00:37:38
of this person maybe will be modified
00:37:40
avi
00:37:42
and there we really have a complication
00:37:46
so one question is this mouse
00:37:48
improper use Belgium the other
00:37:51
question change of
00:37:53
diet we can change for better
00:37:56
and we can change for tyr and we are
00:37:59
we all we are human beings
00:38:01
we are always exposed to this change
00:38:05
we are always exposed to bad
00:38:09
food we are always exposed to
00:38:12
emotional intermittents which will
00:38:15
perhaps change our way of eating
00:38:19
in a deleterious way which will change the
00:38:24
microbiota which as a result can
00:38:26
trigger an informing problem which
00:38:30
will depend on our genetics which will
00:38:34
trigger by example there is auto
00:38:36
immune disease which hashimoto for example you
00:38:41
understand the situation
00:38:42
so that is why it is a
00:38:45
huge subject and which everyone is in the process of
00:38:49
evolving in this direction there the microbes
00:38:52
yom and a regulator of the
00:38:55
inflammatory state of the human being
00:38:58
so I told you that there is this
00:39:02
question of lps what are fps that
00:39:06
of amp
00:39:08
ipo polysaccharides that means that
00:39:12
a high concentration we will see
00:39:16
strong immunological reactions and
00:39:19
fever think with me
00:39:21
think I told you that the lps
00:39:26
and at the level of the bacteria that
00:39:30
had to be shown but I'm showing you
00:39:32
it's not a three-day training as we do like this
00:39:36
because it's a
00:39:38
big training so you understand
00:39:41
I would still like to show you
00:39:44
what exactly the
00:39:46
ps is for me it is made up of three
00:39:50
legrand negatives there are three layers at the
00:39:54
level of air membranes that the
00:39:56
bacteria and large positives do not
00:39:59
all have enough importance what is
00:40:01
a bed popol saccharides ipo
00:40:04
polysaccharides of people there is a
00:40:07
polysaccharide linked to something
00:40:11
lipidic ipo polysaccharides we
00:40:15
agree so this increase in ipo
00:40:18
polysaccharides if it is in the
00:40:20
negative bacteria is considered a
00:40:22
slope which will be seen by our
00:40:27
receptor toll like 4 to put it simply
00:40:31
which is another by testing the lah
00:40:36
in the macrophages of our intestine
00:40:39
it will have a reaction if we have
00:40:42
a lot of the nbs we will have an
00:40:45
even stronger reaction which we can even go
00:40:48
as far as feverish so we will say listen to
00:40:52
me who lp is it because you will
00:40:55
always listen to that there are quite a few
00:40:58
people who have not always
00:41:01
lp it's a india to toxins it is the
00:41:07
jl ps like a doc sands to toxins
00:41:11
so what we actually say is that l ps
00:41:15
and ando toxins are synonymous
00:41:18
hockey because this index is two
00:41:23
teeth it is a toxin which will cause an
00:41:27
internal imbalance
00:41:30
that is metabolic endotoxins
00:41:36
and what was I going to tell you there are
00:41:38
also the receptor complexes yielded
00:41:43
14 these are complete
00:41:48
protein complexes and when we talk about complexes
00:41:52
all that is always proteins this
00:41:54
complex and the 14 that ckoi complex of
00:41:57
14 the complexes of kratos is a
00:42:00
protein which is
00:42:02
produced by macrophages to help
00:42:06
detect the famous think that it's a
00:42:11
detail we also have an anthem of the 2nd of the
00:42:15
two is a protein I invites
00:42:18
people who will make the connection of the bed
00:42:21
polysaccharides of lps with the times the
00:42:25
famous toll like we scepter
00:42:28
we will trigger all that it's
00:42:31
you will see give in all the
00:42:34
time cd that means earth class
00:42:38
differentiations you will need that
00:42:41
to understand the inflammatory process
00:42:46
innate immunity and especially
00:42:49
adaptive immunity if you do not know them
00:42:52
give in the gloucester echo and
00:42:54
differentiation they have several
00:42:55
figures hockey for example this cd art
00:43:00
it is also named its 284 but gradually
00:43:03
and as you go you will know
00:43:05
things but the most important thing is that
00:43:09
because we will rather focus on
00:43:12
lps at low concentrations
00:43:14
which will play a role in
00:43:17
inflammation
00:43:18
induced by
00:43:22
poor diet
00:43:25
you want an example an example is
00:43:28
that when we have trans fatty acids
00:43:31
be careful I'm going in the next
00:43:34
mine explained trans fatty acids because we
00:43:38
produce trans fatty acids ourselves
00:43:39
there are also trans fatty acids
00:43:42
from ruminants and it is to trans fatty acids
00:43:46
quietly realized which for example oleic acid
00:43:52
not heating by poorly
00:43:57
done frying becomes an electrical incident
00:44:01
which is a trans civilian that it does
00:44:04
very badly to another organism and that's why
00:44:08
I am talking to you
00:44:10
there is a link between the information
00:44:14
ps zeal and its fatty acids there
00:44:17
while to remind you that the lps
00:44:21
of large negative and index indo toxins
00:44:24
are two words of expressions that we
00:44:27
can sometimes mix d 'agreement
00:44:31
let's now think in a healthy individual
00:44:35
how it happens in an individual without there
00:44:39
being an uncontrolled increase
00:44:43
in intestinal permeability
00:44:46
intestinal permeability
00:44:48
that means that we are going to have an
00:44:52
opening
00:44:53
isn't it of our connection between
00:44:58
note also and the other normal which will
00:45:01
open and close which will open
00:45:04
and close it is an
00:45:08
uncontrolled increase in intestinal permeability
00:45:11
and the inflammatory response
00:45:16
tnf alpha and interferon gamma
00:45:20
toussaint we go after studied what is
00:45:24
what are interferons kid
00:45:27
what is tnf alpha all that but
00:45:30
finally
00:45:32
inflammatory response
00:45:34
balanced by a regulatory immune response
00:45:37
so you understand we have
00:45:40
an intestinal permeability that it will
00:45:43
give a professional response slaughterhouse and
00:45:45
that everything will become normal again because
00:45:48
in the name of molecules which will regulate all
00:45:53
that like tgf beta and the famous retinoic acid
00:46:00
and also that I am leaving myself intelligent who
00:46:02
say for example who will give
00:46:04
this this repair and there you will tell me
00:46:07
help but how I understand nothing
00:46:09
because it will trigger
00:46:14
regulatory t cells
00:46:17
lymphocytes t the names it already says
00:46:21
regulatory t cells
00:46:24
the noodles already will regulate
00:46:27
the inflammation which we call very gay
00:46:30
so there it is chapters and
00:46:33
chapters on the information but what
00:46:37
is more important that you begin to
00:46:39
understand is that physiologically we have
00:46:42
an increase in permeability if
00:46:46
we have an increase we have a response to
00:46:48
take shape and war but there are two
00:46:50
regulatory immune responses which will say
00:46:54
give differentiation into a
00:46:57
transformation of lymphocytes t a
00:47:02
lymphocyte created regulatory it is a
00:47:07
type of lymphocytes and which is the very
00:47:09
cheerful and there everything will recover from a
00:47:13
phase we will arrive at a good time so
00:47:17
you observe observed that we have an access
00:47:20
the inflammatory accelerator and an
00:47:22
inflammatory braker who knows this
00:47:25
rule so he will we will play with
00:47:29
accelerator braker accelerator
00:47:32
shiver and we need that because I
00:47:34
told you that an inflammation and a
00:47:37
healing process isn't it
00:47:40
so this will happen all the time
00:47:44
that they do not enter body needs to
00:47:47
defend itself everything is good now we will
00:47:51
see in an individual an
00:47:53
imbalance an imbalance we will
00:47:57
break the balance of external factors
00:48:02
we will break this balance
00:48:05
either by a genetic polymorphism a
00:48:08
slip I don't know there will be a
00:48:12
super
00:48:14
inflammatory permeability and therefore we
00:48:18
will have an increase enough to
00:48:21
exacerbate the inflammatory response
00:48:24
so you can see that it all starts
00:48:26
here in this first a square that I
00:48:30
put for you and there we will have an
00:48:33
increase in intestinal permeability
00:48:36
isn't it going to give me what
00:48:39
the chronic inflammatory state all the
00:48:43
time and there we will have our famous
00:48:48
pathological table and there it will have
00:48:52
the whole list that I showed you
00:48:55
so we needs an
00:48:58
external imbalance or a polymorphism and a
00:49:02
genetic polymorphism
00:49:04
what can cause all this there are
00:49:08
several factors that will cause
00:49:11
wanted one obesity you want
00:49:14
another unsuitable diet a
00:49:17
pro inflammatory diet there are
00:49:21
several factors which will cause
00:49:24
imbalances you want the other
00:49:27
stresses excessive stress
00:49:29
chronic stress
00:49:31
you see there are all these factors which
00:49:36
will act we can have a good ali
00:49:39
genetic morphism obviously which will
00:49:41
trigger an illness autoimmune
00:49:43
obviously so all that is like that
00:49:47
it is a multitude of factors which will
00:49:49
lead us to the pathology but the
00:49:51
pathology can also lead us to
00:49:54
fuel this chronic inflammatory state
00:49:56
and that is the great
00:49:58
difficulty now I am going to
00:50:01
show you something from the
00:50:05
Brazilian institute of our functional spy
00:50:09
as well as I do not like to steal things that
00:50:13
do not belong to me but that house
00:50:16
this brochure that I find very very
00:50:19
good I decided to share with you
00:50:22
even in Portuguese because the words
00:50:26
are very very similar you will
00:50:29
see so influence of the intestinal microbiota
00:50:34
look at that it's a Portuguese but you
00:50:37
can still understand that's why
00:50:39
I allowed myself to put this
00:50:42
brochure from the Brazilian institute of
00:50:46
our and are functional so
00:50:49
let's
00:50:51
see here there is this side which is a
00:50:55
side here I have an obese family ok so
00:51:04
intestinal microbiota
00:51:06
of the obese person
00:51:10
with 10 bios ok that's a
00:51:16
telling example that when we have a bickering
00:51:20
I don't want to say that there are only
00:51:26
obese people who have said to you, including you, but
00:51:29
there are very, very thin people
00:51:32
who will also have the so-called bios, but
00:51:35
one will have ten bios with the composition
00:51:40
of the modified intestinal flora.
00:51:42
altered fermentation process
00:51:46
has altered because our microbiota our
00:51:50
fermentable bacteria will
00:51:53
work much more so we will not have
00:51:56
what we will have fermentation honorat
00:51:59
bloating we will have all the signs and
00:52:03
symptoms so if we have a person who is
00:52:06
not bad but clemency ikela
00:52:09
the same sign of 10 bios airlines violent gesture
00:52:14
increase in energy demand
00:52:17
what is in our case here
00:52:20
increase in insulin resistance
00:52:23
the question is that we have
00:52:28
two first suites and we have inflammation
00:52:32
of one side and we have insulin on the other
00:52:36
side 1 underlines listen to me insulin the
00:52:41
metabolic pathway of insulin we are going to
00:52:45
use a slap tyrosine kinase and
00:52:48
the inflammatory voice we are going to use
00:52:51
capable students which is also from
00:52:55
kinases y kaka and so the kinases
00:52:59
can
00:53:01
cross so we will have inflammation
00:53:04
associated with insulin resistance
00:53:08
resistance in soul iniic associate an
00:53:11
inflammatory process and what does
00:53:14
that give to the glands tation of the
00:53:17
formation decrease in satiety and there
00:53:21
obviously we can talk about two hormones
00:53:24
who will act but that is not our
00:53:26
objective
00:53:27
today our objective is to
00:53:29
show you that from the intestine of one
00:53:34
of the simulation honors
00:53:38
the inflammation at the cerebral level
00:53:42
adipose tissue times muscle is obviously too
00:53:46
long and undecided where grosso and collomb
00:53:50
you see the problem from
00:53:55
this microbiota 1 ghz but to the
00:53:58
increases in inflammation
00:54:00
reduction of society increase
00:54:04
by lps I explained to you its
00:54:07
incorporation of very diligent serol
00:54:10
increase in costs specified rolls
00:54:13
and who knows triglycerides
00:54:16
obviously increase in the invitation
00:54:18
of the macrophages because I told you
00:54:21
that the macrophages have receptors for
00:54:24
dance and pop models it is that
00:54:28
it is the lps if there is an increase
00:54:31
in the lps there is an increase of
00:54:34
the infiltration of macrophages
00:54:36
increase in the invitation of
00:54:39
macrophages and steatosis there on a level
00:54:42
of the liver is 14 non-alcoholic hepatic
00:54:46
obviously you are going to have the new
00:54:49
lipogenesis in elisa but that means that
00:54:52
everyone who has induced this woody
00:54:55
decline will see hepatic steatosis
00:54:57
no what will play
00:55:01
individualized biochemistry he will not see
00:55:03
steatosis but he will have
00:55:05
information at the level of the brain he will
00:55:09
have information at the level of the
00:55:11
adipose tissue or pdf he will see this famous
00:55:14
non-alcoholic fatty liver disease
00:55:17
and there we will have an increase in what is
00:55:21
non-alcoholic of all the
00:55:24
hepatic markers in slats as haste and increases
00:55:29
increase in neither too much nor too much
00:55:32
sidaction what is that glycation we to
00:55:35
glycation can have an
00:55:38
oxidative obligation know stress oxidative you will be
00:55:42
extracted stress nor too active by an
00:55:45
excess of increase of has high to the
00:55:50
oxidation decrease of the oxidation of
00:55:53
fatty acids to a [ __ ] and the voice
00:55:56
fiap also jimmy jimmy mission of the
00:56:00
production of our famous butyrate at the
00:56:02
level of our colons I would like to
00:56:06
tell you that the mp cassette one voice it is
00:56:08
important to say that it will decrease
00:56:10
because it is a pathway which allows the
00:56:14
translocation of groot 4 none which is
00:56:18
at the level of his two ears which goes
00:56:20
to the membrane to allow
00:56:22
the entry of glucose through
00:56:25
another 4
00:56:26
it is its only case there and therefore if
00:56:28
you have a reduction you have an
00:56:30
increase in insulin resistance
00:56:33
reduction in secretion of a Christian
00:56:36
anchored team to them we you know we have incretins
00:56:40
igl don't we have two drugs
00:56:45
which will control me these incretins
00:56:47
for diabetics bags are now
00:56:51
they which are produced at the level of
00:56:53
human rights reduction of the ink
00:56:56
which goes what control
00:56:59
gastric emptying which will also
00:57:03
cretinize it will quiz
00:57:07
increase the production of insulin by
00:57:10
the pancreas if you have a decrease
00:57:12
in creative you have a decrease in
00:57:15
solim
00:57:16
epithelial permeability increased glp
00:57:20
years is an example of a Christian is
00:57:23
also will play 7 g/l perrin at the level of the
00:57:28
pancreas in the direct production
00:57:31
of insulin why because the
00:57:33
pancreas one of glp receptors
00:57:36
all this will be
00:57:41
potentiated by the use of 1
00:57:45
biotics and anti-inflammatories
00:57:48
here I quite simply have a example of
00:57:53
biotic silos we haven't talked about that
00:57:55
which are also one of the causes that I
00:57:59
'm going to explain to you which will increase
00:58:02
inflammation isn't it
00:58:04
pesticides we have here our human
00:58:08
intestinal lome it's the cavity everything
00:58:11
that is invited we call itself
00:58:12
interested in the intestinal cavity
00:58:15
with our microbiota if you are
00:58:18
unbalanced if you make a provision
00:58:20
here for these new ones must not forget
00:58:22
that we also have the mucus will have an
00:58:26
infiltration of bacteria lp is what
00:58:30
I would not like to
00:58:32
enter xenobiotics return of lp
00:58:37
increase of lps presence a format
00:58:40
thouars on the other hand
00:58:43
so what I would like to tell you is
00:58:46
that we can evaluate the inflammatory state
00:58:48
at the level of the liver the gammas gt we
00:58:52
consider that we considers no the
00:58:55
doctor considers from an epidemiological point of view
00:59:01
that above 40 yes we have a
00:59:06
problem on the
00:59:07
other hand we of nutrition
00:59:09
function we have no value which we
00:59:11
call optimal value and for us the
00:59:15
optimal value to be sure that 'there
00:59:17
is no information it's a top of 16
00:59:22
or and
00:59:24
let's look at the other side the other side
00:59:27
it's quite the opposite
00:59:29
the other side we're going to talk about
00:59:32
intestinal microbiota
00:59:34
and others at the ficg said burrows and to the
00:59:38
marbles to the
00:59:40
110 bios you see it's not complicated
00:59:42
to understand Portuguese
00:59:45
what we are going to see at the level of the
00:59:47
brain reduction of inflammation
00:59:51
increase regulated to
00:59:54
regulate the society is also not
00:59:57
not being hungry at all comes from
00:59:58
having to can so we will see all
01:00:01
the opposites
01:00:04
improvement in detoxification
01:00:06
reduction in
01:00:08
macrophage infiltration production of boutis spleen
01:00:11
what I would like to tell you what is the most
01:00:13
important reduction in insulin resistance
01:00:16
it is that one another functions
01:00:19
and the work in the process of transforming
01:00:23
this situation into this situation
01:00:27
ok so what are we going to see as a
01:00:31
consequence of that we will have looked with
01:00:36
me at
01:00:37
probiotics and prebiotics which will
01:00:40
simply have
01:00:43
the prevention of the entry of lps
01:00:46
the prevention of excel biotic that
01:00:48
means much more less quantity and
01:00:52
we will have a logical answer 6 you as
01:00:55
I showed you with our
01:00:59
line of
01:01:01
2
01:01:04
the arrows there that I showed you
01:01:06
impatience years and a patient who has
01:01:08
problems alterations who does
01:01:11
not know a balance so that's what
01:01:15
I would like to show you and
01:01:18
our next time we are going to talk about
01:01:22
pesticides and other Paulois we're going to
01:01:24
talk about all that I don't know if we
01:01:28
'll have a bread part iii but I
01:01:30
'm in no hurry the goal is that
01:01:33
you'll get the best that I can
01:01:36
give you a free term here on
01:01:41
instagram facebook and youtube I
01:01:44
wish you an excellent evening
01:01:48
and first of all I am going to ask you
01:01:52
something
01:01:53
like I ask you to give a like if
01:01:58
you think it is worth it and I
01:02:01
also ask you to invite your
01:02:03
colleagues your professional colleagues
01:02:05
to come watch our live you know
01:02:09
why because if you call a
01:02:11
colleague you can chat with him
01:02:13
after you can share with him you
01:02:16
can treat yourself would not resolve any
01:02:19
doubt between you making
01:02:21
mental maps for you that's why and I
01:02:24
couldn't let to tell you
01:02:27
another thing if you want to have all the
01:02:32
sto rick of our project 19/09 it's
01:02:38
very simple you will register
01:02:41
for free
01:02:42
in the marceau academy and you must have had the
01:02:46
first day until now when
01:02:49
we started this project by order I
01:02:52
think it's more without that
01:02:56
searched by everyone especially Facebook
01:02:58
Instagram but you do as you
01:03:01
want it's very simple you
01:03:04
type academy marceau and you immediately find
01:03:08
ok and so we continue you see
01:03:12
that to explain the trigger there is at
01:03:16
all ages and explain one that it is the
01:03:19
microbiome the other will be the pesticides
01:03:22
then we are
01:03:24
not going to go through a few years ago which I
01:03:27
am not going to
01:03:28
explain too much because they are
01:03:31
obvious
01:03:32
and there are some others which are too
01:03:34
complex that I will just say hello
01:03:36
but they are the list this one there are
01:03:40
others
01:03:41
thank you thank you see you
01:03:44
soon
01:03:48
20 like heroes
01:03:51
[Music]

Description:

Live 19-29 #25 - L’INFLAMMATION ET SES 10 DÉCLENCHEURS – Partie1 --- Cette vidéo est l'enregistrement du Live 19-29 #25 --- L’INFLAMMATION ET SES 10 DÉCLENCHEURS – Partie1 Je suis Elisa Marsaud, chirurgien-dentiste, naturopathe et formatrice spécialisée en Nutrition Fonctionnelle. Je vous montre comment appliquer de A à Z la Nutrition Fonctionnelle pour transformer des vies : la vôtre et celle de vos patients/clients. Live 19-29 est notre point de rencontre à 19h29, 100% ON LINE, 100% GRATUIT Où je vous présente comment vous pouvez appliquer la Nutrition Fonctionnelle dans votre activité professionnelle de santé. Venez nous rejoindre tous les mardis et jeudi à 19h29 sur mes chaînes : YouTube: https://www.youtube.com/channel/UCwC9Pcf4_EMtzZ44KuW1bPw VEM COMIGO. Elisa Marsaud

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