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Download "Michael Levin - Plasticity w/out genetic change: bioelectric embryos & synthetic proto-organisms"

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"videoThumbnail Michael Levin - Plasticity w/out genetic change: bioelectric embryos & synthetic proto-organisms
Table of contents
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Table of contents

0:00
Intro
2:32
Knowledge Gaps: prediction
3:32
The State of the Art
4:34
Where is Anatomical Pattern Specified?
6:51
Same anatomy, despite perturbations
13:53
Somatic electrical activity is the cognitive medium of morphogenetic decision-making
14:59
Writing High-level Setpoints into Cellular CI
16:42
Endogenous membrane voltage pattern is crucial for Xenopus embryonic brain patterning
19:52
Re-writing Target Morphology
20:17
Bioelectrically-Encoded Pattern Memory
22:04
An organism's genome sets its Target Morphology, doesn't it?
23:58
Developing Quantitative, Predictive Multiscale
24:47
Machine Learning for Model Discovery
25:18
Cell Collectives can pursue Target Morphologies other than their Genomic Default
26:21
Biomedical Applications
27:12
Synthetic Morphology: probing the creativity of cellular collective intelligence
28:02
Xenobots - a novel proto-organism
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Video tags

ipam
math
mathematics
ucla
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Description:

Recorded 17 February 2022. Michael Levin of Tufts University presents "Structural and functional plasticity without genetic change: from bioelectric embryos to synthetic proto-organisms" at IPAM's Mathematics of Collective Intelligence Workshop. Abstract: The highly robust and consistent outcomes of embryogenesis and regeneration in standard model systems obscure an important property of life: plasticity under novel circumstances. In this talk we will briefly review some examples of morphogenesis adjusting to perturbations of environment and internal composition, which highlights novel aspects of emergent morphogenetic control and the evolution thereof. We will show how AI-driven reconfiguration of embryonically liberated biological tissue can lead to new organisms that exhibit collective behaviors previously unseen in nature, such as kinematic self-replication. We will conclude by showing how these behaviors do not respect the human-created distinctions between genotype and phenotype, brain and body, and tape and machine. Learn more online at: http://www.ipam.ucla.edu/programs/workshops/mathematics-of-intelligences/?tab=schedule

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